Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249765 | 0.81 | ADORA3 (0.37) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL7351412 | 0.81 | ADORA3 (0.37) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL5437820 | 0.80 | TSHR (0.31) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL3286085 | 0.77 | LMNA (0.36) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL29098162 | 0.76 | TSHR (0.31) | ALDH1A1TSHRCYP2D6CYP2C19HIF1A | |
| SCHEMBL10811536 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TRPA1 | |
| SCHEMBL25285985 | 0.74 | PKM (0.30) | — | |
| SCHEMBL11246102 | 0.74 | MMP8 (0.44) | — | |
| SCHEMBL3285404 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL13412398 | 0.72 | ALDH1A1 (0.38) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004354-A1 | ALKOXYSILYL FUNCTIONAL OLIGOMERS AND PARTICLES SURFACE-MODIFIED THEREWITH | WACKER CHEMIE AG (DE) | 2010-01-07 | — | — | US | disclosed |
| EP-2032613-A2 | ALKOXYSILYL FUNCTIONAL OLIGOMERS AND PARTICLES SURFACE-MODIFIED THEREWITH | Wacker Chemie AG (DE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008000674-A2 | ALKOXYSILYL FUNCTIONAL OLIGOMERS AND PARTICLES SURFACE-MODIFIED THEREWITH | WACKER CHEMIE AG (DE) | 2008-01-03 | — | — | WO | disclosed |