⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389921 | 0.76 | — | — | |
| SCHEMBL31389636 | 0.67 | POLB (0.36) | — | |
| SCHEMBL31389529 | 0.67 | CCR5 (0.47) | — | |
| SCHEMBL31389471 | 0.64 | CYP11B2 (0.36) | — | |
| SCHEMBL31389550 | 0.64 | POLB (0.37) | — | |
| SCHEMBL31389485 | 0.64 | POLB (0.58) | — | |
| SCHEMBL31389849 | 0.64 | RPS6KA5 (0.38) | — | |
| SCHEMBL31389433 | 0.59 | SPR (0.32) | — | |
| SCHEMBL20337748 | 0.59 | TSHR (0.38) | — | |
| SCHEMBL31389544 | 0.56 | CDK5 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043225-A2 | DEGRADERS OF CYCLIN-DEPENDENT KINASE 2 | GENENTECH, INC. (US) | 2025-02-27 | — | — | WO | disclosed |