Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | MC5R | P33032 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30985268 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2A6SIGMAR1TDP1HRH3 | |
| SCHEMBL19116113 | 0.93 | TDP1 (0.50) | CYP1A2CYP2A6SIGMAR1TDP1HRH3 | |
| SCHEMBL27938396 | 0.91 | TDP1 (0.48) | CYP1A2CYP2A6SIGMAR1TDP1HRH3 | |
| Acetic Acid SCHEMBL27771808 | 0.87 | CYP1A2 (0.58) | CYP1A2CYP2A6SIGMAR1TDP1HDAC1 | |
| SCHEMBL80282 | 0.87 | SIGMAR1 (0.59) | CYP1A2CYP2A6SIGMAR1HRH3HDAC1 | |
| SCHEMBL6240981 | 0.85 | CYP1A2 (0.65) | CYP1A2CYP2A6SIGMAR1HRH3SLC6A4 | |
| SCHEMBL29560700 | 0.85 | CYP1A2 (0.65) | CYP1A2CYP2A6SIGMAR1HRH3SLC6A4 | |
| SCHEMBL9129308 | 0.85 | SIGMAR1 (0.58) | CYP1A2CYP2A6SIGMAR1HRH3HDAC1 | |
| Benzaldehyde SCHEMBL27720726 | 0.84 | RAB9A (0.55) | CYP1A2CYP2A6SIGMAR1TDP1HRH3 | |
| SCHEMBL7621730 | 0.84 | SIGMAR1 (0.56) | CYP1A2CYP2A6SIGMAR1HRH3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112771684-B | Ink composition for manufacturing organic semiconductor device | 株式会社大赛璐 | 2024-07-12 | — | — | CN | claimed |
| EP-0950052-B1 | METHOD FOR PREPARING A TETRAHYDROPYRIDIN DERIVATIVE | SANOFI SYNTHELABO (FR) | 2004-09-08 | — | — | EP | claimed |
| US-6118006-A | REACTING 4-(3-TRIFLUOROMETHYLPHENYL)-1,2,3,6-TETRAHYDROPYRIDINE WITH2-(2-BROMOETHYL)NAPHTHALENE | SANOFI-SYNTHELABO (FR) | 2000-09-12 | — | — | US | claimed |
| EP-0950052-A1 | METHOD FOR PREPARING A TETRAHYDROPYRIDIN DERIVATIVE | SANOFI-SYNTHELABO (FR) | 1999-10-20 | — | — | EP | claimed |
| WO-1998028273-A1 | METHOD FOR PREPARING A TETRAHYDROPYRIDIN DERIVATIVE | SANOFI (FR) | 1998-07-02 | — | — | WO | claimed |
| WO-2024218171-A1 | COMPOUNDS WITH ACTIVITY AGAINST SARS-COV-2 | NATIONAL HELLENIC RESEARCH FOUNDATION (GR) | 2024-10-24 | — | — | WO | disclosed |
| US-11192907-B2 | Aminopeptidase A inhibitors and pharmaceutical compositions comprising the same | QUANTUM GENOMICS (FR) | 2021-12-07 | — | — | US | disclosed |
| US-20210309678-A1 | AMINOPEPTIDASE A INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Institut National de la Santé et de la Recherche Médicale (FR) | 2021-10-07 | — | — | US | disclosed |
| US-20210300953-A1 | OPTICALLY-ACTIVE CYCLOPENTENONE DERIVATIVES | TOHOKU UNIVERSITY (JP) | 2021-09-30 | — | — | US | disclosed |
| CN-113166182-A | Aminopeptidase A inhibitor and pharmaceutical composition comprising the same | 量子基因公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020059646-A1 | OPTICALLY-ACTIVE CYCLOPENTENONE DERIVATIVES | 国立大学法人東北大学 | 2020-03-26 | — | — | WO | disclosed |
| US-10364226-B2 | Pyridazinone compounds and uses thereof | ALIOS BIOPHARMA, INC. (US) | 2019-07-30 | — | — | US | disclosed |
| US-4705871-A | Aralkoxy and aryloxyalkoxy kojic acid derivatives | G. D. SEARLE & CO. (US) | 1987-11-10 | — | — | US | disclosed |
| CN-86105870-A | Band 5-amino-2, the blood vessel tension peptide protoenzyme inhibitor of 5-two replacement-4-hydroxypentanoic acid bases | — | 1987-03-11 | — | — | CN | disclosed |
| US-4644071-A | Aralkoxy and aryloxyalkoxy kojic acid derivatives | G. D. SEARLE & CO. (US) | 1987-02-17 | — | — | US | disclosed |
| US-4528195-A | Imidazole derivatives and salts thereof, their synthesis and intermediates and pharmaceutical formulations | THOROGOOD PETER B (GB) | 1985-07-09 | — | — | US | disclosed |
| US-4468514-A | Preparation of 3-bromocephalosporins from thiazoline azetidinones | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | disclosed |
| EP-0003560-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-02 | — | — | EP | disclosed |
| US-4416895-A | ANTICOAGULANTS, ANTISHOCK AGENTS | BURROUGHS WELLCOME CO. (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0003560-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192907-B2 | Aminopeptidase A inhibitors and pharmaceutical compositions comprising the same | ANPEP, DNPEP, ENPEP | CYP1A2 3100/4885CYP2A6 2296/4885SIGMAR1 4816/4885 |
| US-20210300953-A1 | OPTICALLY-ACTIVE CYCLOPENTENONE DERIVATIVES | PTGIS, PTGES, PTGES2 | CYP1A2 217/4885CYP2A6 146/4885SIGMAR1 4101/4885 |
| US-20210309678-A1 | AMINOPEPTIDASE A INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | ANPEP, DNPEP, ENPEP | CYP1A2 3100/4885CYP2A6 2296/4885SIGMAR1 4816/4885 |
| US-10364226-B2 | Pyridazinone compounds and uses thereof | PDXK, PNPO, PLPBP | CYP1A2 642/4885CYP2A6 622/4885SIGMAR1 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.