Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325847 | 0.88 | MAPT (0.64) | LMNAMAPTL3MBTL1KDM4ENPSR1 | |
| SCHEMBL31407246 | 0.83 | L3MBTL1 (0.63) | LMNAMAPTL3MBTL1RAB9AKMT2A | |
| SCHEMBL658106 | 0.83 | MAPT (0.64) | LMNAMAPTL3MBTL1KDM4ENPSR1 | |
| SCHEMBL31407236 | 0.81 | NOTUM (0.54) | MAPTL3MBTL1SLC2A1GRM4KMT2A | |
| SCHEMBL3868073 | 0.81 | MAPT (0.63) | LMNAMAPTL3MBTL1KDM4ENPSR1 | |
| SCHEMBL6319805 | 0.80 | MAPT (0.68) | LMNAMAPTL3MBTL1KDM4ENPSR1 | |
| SCHEMBL6204121 | 0.80 | LMNA (0.64) | LMNAMAPTL3MBTL1KDM4ENPSR1 | |
| SCHEMBL6321338 | 0.80 | MAPT (0.64) | LMNAMAPTL3MBTL1KDM4ESLC2A1 | |
| SCHEMBL6328277 | 0.80 | MAPT (0.64) | LMNAMAPTL3MBTL1KDM4ESLC2A1 | |
| SCHEMBL6202777 | 0.80 | MAPT (0.64) | LMNAMAPTL3MBTL1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743455-A1 | SARM1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012296-A1 | SARM1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-16 | — | — | WO | disclosed |