SCHEMBL31409153

SCHEMBL31409153

O=C1c2ccccc2CC(c2cccc(F)c2)N1c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.50
TSHR P16473 1/20 0.46
NOS3 P29474 1/20 0.45
ALDH1A1 P00352 2/20 0.44
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
MAPT P10636 3/20 0.41
LMNA P02545 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP19A1 P11511 1/20 0.40
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
PGR P06401 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31409136 0.86 RAB9A (0.47) LMNAMEN1KMT2AKDM4EGAA
SCHEMBL31409122 0.81 KMT2A (0.53) ALDH1A1MAPTMEN1KMT2AGAA
SCHEMBL31409167 0.74 RAB9A (0.51) GFERTSHRALDH1A1MAOAMAPT
SCHEMBL31409141 0.74 ALDH1A1 (0.55) GFERTSHRALDH1A1MAPTMEN1
SCHEMBL22691615 0.72 GFER (0.56) GFERALDH1A1MAPTLMNAMEN1
SCHEMBL31409134 0.69 ACHE (0.44) ALDH1A1LMNAMEN1KMT2AKDM4E
SCHEMBL22691868 0.69 GFER (0.50) GFERTSHRALDH1A1MAPTLMNA
SCHEMBL22691888 0.69 GFER (0.47) GFERALDH1A1MAPTLMNAMEN1
SCHEMBL31409139 0.69 HSD11B1 (0.49) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL29164929 0.69 LMNA (0.65) NOS3ALDH1A1MAOBLMNACYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119506909-A Method for electrochemically synthesizing 3, 4-dihydro-isoquinoline-1 (2H) -ketone compound 宜宾学院 2025-02-25 CN disclosed