SCHEMBL3141175

SCHEMBL3141175

COc1cccc(S(OS(=O)(=O)c2ccc(C)cc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.47
PGR P06401 3/20 0.45
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MAPT P10636 2/20 0.44
TP53 P04637 2/20 0.44
KEAP1 Q14145 2/20 0.44
NFE2L2 Q16236 2/20 0.44
POLB P06746 1/20 0.44
TAS2R14 Q9NYV8 1/20 0.43
HSD11B1 P28845 1/20 0.42
ACHE P22303 2/20 0.42
BCHE P06276 1/20 0.42
LMNA P02545 1/20 0.41
CTSG P08311 1/20 0.41
CMA1 P23946 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3143801 0.88 LMNA (0.51) HTTSMN1; SMN2MAPTKEAP1POLB
SCHEMBL759994 0.88 LMNA (0.51) HTTSMN1; SMN2MAPTKEAP1POLB
SCHEMBL8903648 0.87 FFAR4 (0.41) FFAR4PGRHTTMAPTTP53
SCHEMBL3136672 0.85 HTT (0.44) HTTSMN1; SMN2KEAP1NFE2L2ACHE
SCHEMBL6757964 0.85 HTT (0.41) HTTSMN1; SMN2KEAP1NFE2L2ACHE
SCHEMBL8078746 0.85 HTT (0.41) HTTSMN1; SMN2KEAP1NFE2L2ACHE
SCHEMBL2955938 0.85 VDR (0.49) HTTSMN1; SMN2KEAP1NFE2L2ACHE
SCHEMBL2962485 0.85 VDR (0.49) HTTSMN1; SMN2KEAP1NFE2L2ACHE
SCHEMBL2964106 0.85 VDR (0.49) HTTSMN1; SMN2KEAP1NFE2L2ACHE
SCHEMBL3144536 0.85 VDR (0.49) HTTSMN1; SMN2KEAP1NFE2L2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1676835-B1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT WAKO PURE CHEM IND LTD (JP) 2014-12-10 EP disclosed
US-7642368-B2 for use as acid generator in semiconductor manufacture; triarylsulfonium salt having a structure that only one aromatic ring of three is different, in a high yield and by-product inhibition; reacting a diaryl sulfoxide with an aryl Grignard reagent in presence of chlorotrialkylsilane and strong acid WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-05 US disclosed
EP-1676835-A1 PROCESS FOR PRODUCING TRIARYLSULFONIUM SALT Wako Pure Chemical Industries, Ltd. (JP) 2006-07-05 EP disclosed