SCHEMBL3141670

SCHEMBL3141670

CC(C)c1ccc(/C=C/C(=O)O)c(C(C)C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.57
MAPK1 P28482 1/20 0.57
TYR P14679 2/20 0.45
FABP3 P05413 1/20 0.44
FABP4 P15090 1/20 0.44
RXRA P19793 1/20 0.44
NR4A2 P43354 1/20 0.44
MIF P14174 1/20 0.42
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA4 P22748 2/20 0.40
NFKB1 P19838 1/20 0.40
ALDH1A1 P00352 1/20 0.39
GAA P10253 1/20 0.39
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
RNASEH1 O60930 1/20 0.39
CA12 O43570 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL525375 1.00 KDM4E (0.57) KDM4EMAPK1TYRFABP3FABP4
SCHEMBL29046248 0.89 KDM4E (0.47) KDM4EMAPK1NFKB1ALDH1A1GAA
SCHEMBL3145961 0.87 KDM4E (0.57) KDM4EMAPK1TYRFABP3FABP4
SCHEMBL3145956 0.87 KDM4E (0.57) KDM4EMAPK1TYRFABP3FABP4
SCHEMBL28319094 0.85 TYR (0.44) KDM4EMAPK1TYRFABP3FABP4
E-Methyl Cinnamate SCHEMBL28810582 0.83 KDM4E (0.51) KDM4EMAPK1TYRRXRANR4A2
E-Methyl Cinnamate SCHEMBL28948986 0.83 KDM4E (0.51) KDM4EMAPK1TYRRXRANR4A2
SCHEMBL12597166 0.83 KDM4E (0.57) KDM4EMAPK1TYRRXRANR4A2
SCHEMBL157462 0.83 ALDH1A1 (0.48) KDM4EMAPK1TYRFABP3FABP4
SCHEMBL645927 0.83 ALDH1A1 (0.48) KDM4EMAPK1TYRFABP3FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230055665-A1 DELIVERY CARRIER INTO CELL ITO, KABUSIKIKAISYA (JP) 2023-02-23 US claimed
EP-2876120-B1 (DIISOPROPYL FUMARATE)-(CINNAMIC ACID DERIVATIVE) COPOLYMER, AND PHASE DIFFERENCE FILM PRODUCED USING SAME TOSOH CORP (JP) 2017-09-06 EP claimed
US-20230055665-A1 DELIVERY CARRIER INTO CELL ITO, KABUSIKIKAISYA (JP) 2023-02-23 US disclosed
CN-111372551-A Gel sheet for skin adhesion 株式会社高丝 2020-07-03 CN disclosed
EP-3542783-A1 OILY COMPOSITION AND OILY COSMETIC Shiseido Company Ltd. (JP) 2019-09-25 EP disclosed
CN-109922784-A OILY COMPOSITION AND OILY COSMETIC 株式会社资生堂 2019-06-21 CN disclosed
CN-109415627-A Zinc oxide fluorophor and its manufacturing method 堺化学工业株式会社 2019-03-01 CN disclosed
CN-107613950-A Sebum adsorbent and the cosmetic preparation containing the sebum adsorbent 堺化学工业株式会社 2018-01-19 CN disclosed
US-20100075882-A1 External Skin Preparation And Skin Cleanser SHISEIDO COMPANY LTD. (JP) 2010-03-25 US disclosed
CN-1135767-A Shield ultraviolet compounded particle and production method thereof and cosmetics thereof KAO CORP (JP) 1996-11-13 CN disclosed
EP-0721484-A1 ULTRAVIOLET SHIELDING COMPOSITE FINE PARTICLES, METHOD FOR PRODUCING THE SAME, AND COSMETICS Kao Corporation (JP) 1996-07-17 EP disclosed
WO-1995009895-A1 ULTRAVIOLET SHIELDING COMPOSITE FINE PARTICLES, METHOD FOR PRODUCING THE SAME, AND COSMETICS KAO CORPORATION (JP) 1995-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230055665-A1 DELIVERY CARRIER INTO CELL CTSA, ATG4A, ATG7 KDM4E 3872/4885MAPK1 4175/4885TYR 3775/4885
US-20100075882-A1 External Skin Preparation And Skin Cleanser CUTA, AOC2, AKR1B10 KDM4E 82/4885MAPK1 2355/4885TYR 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.