Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31712882 | 0.74 | RET (0.44) | RETNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL31712871 | 0.74 | NNMT (0.40) | NPC1RAB9ACYP11B2ALDH1A1HPGD | |
| SCHEMBL30024398 | 0.73 | PLK1 (0.47) | NPC1RAB9AALDH1A1GAAHTT | |
| SCHEMBL31425751 | 0.72 | PLK1 (0.66) | NPC1RAB9AALDH1A1GAAHTT | |
| SCHEMBL30025133 | 0.72 | PLK1 (0.66) | NPC1RAB9AALDH1A1GAAHTT | |
| SCHEMBL24468528 | 0.71 | CYP1A2 (0.45) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL29685367 | 0.65 | IP6K1 (0.43) | SMYD3MAPK14 | |
| SCHEMBL9097938 | 0.64 | ACHE (0.48) | ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL9096010 | 0.64 | GLA (0.46) | ALDH1A1KMT2AGAAKDM4EHPGD | |
| SCHEMBL24169997 | 0.62 | ALDH1A1 (0.58) | NPC1RAB9AALDH1A1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119552151-B | PRMT5 inhibitors and uses thereof | 赛岚(杭州)生物医药科技有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-119552151-A | Novel PRMT5 inhibitors and uses thereof | 赛岚(杭州)生物医药科技有限公司 | 2025-03-04 | — | — | CN | disclosed |