Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31455206 | 0.88 | CHRM2 (0.38) | PRKAA2SYKCHRM2CHRM1CHRM3 | |
| SCHEMBL31455407 | 0.79 | GSK3B (0.35) | GSK3AGSK3BAURKACYP2C19PLK1 | |
| SCHEMBL31455013 | 0.75 | GSK3B (0.44) | GSK3AGSK3BAURKACYP2C19MEN1 | |
| SCHEMBL31455591 | 0.75 | GSK3B (0.39) | GSK3AGSK3BAURKACYP2C19MEN1 | |
| SCHEMBL31455328 | 0.75 | DRD4 (0.44) | FAAHACHESYKSIGMAR1 | |
| SCHEMBL30802389 | 0.74 | SIGMAR1 (0.46) | PRKAA2SIGMAR1MEN1KMT2A | |
| SCHEMBL27226835 | 0.74 | SIGMAR1 (0.46) | PRKAA2SIGMAR1MEN1KMT2A | |
| SCHEMBL31455198 | 0.73 | SIGMAR1 (0.41) | FAAHACHESYKCYP2D6SIGMAR1 | |
| SCHEMBL31455247 | 0.73 | PIN1 (0.46) | GSK3AGSK3BAURKACYP2C19MEN1 | |
| SCHEMBL31455412 | 0.73 | GSK3B (0.43) | GSK3AGSK3BAURKACYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059577-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS | ATAVISTIK BIO, INC. (US) | 2025-03-20 | — | — | WO | disclosed |