Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31465843 | 0.88 | SIGMAR1 (0.47) | SIGMAR1KCNH2HTR2B | |
| SCHEMBL31466615 | 0.86 | SIGMAR1 (0.45) | SIGMAR1KCNH2HTR2B | |
| SCHEMBL31466107 | 0.85 | SIGMAR1 (0.44) | SIGMAR1KCNH2HTR2BCYP2C19DRD2 | |
| SCHEMBL31465985 | 0.83 | ABL1 (0.46) | SIGMAR1KCNH2HTR2BDRD2 | |
| SCHEMBL31465980 | 0.83 | SIGMAR1 (0.44) | SIGMAR1KCNH2HTR2B | |
| SCHEMBL12328889 | 0.82 | POLB (0.43) | CYP2C19 | |
| SCHEMBL14686768 | 0.80 | PRCP (0.57) | SIGMAR1DRD2 | |
| SCHEMBL31466526 | 0.79 | DRD2 (0.40) | SIGMAR1KCNH2HTR2BACHEDRD2 | |
| SCHEMBL31465999 | 0.79 | SIGMAR1 (0.54) | SIGMAR1KCNH2HTR2BCYP1A2CYP2C19 | |
| SCHEMBL16827947 | 0.76 | TP53 (0.41) | SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |