Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31466526 | 0.90 | DRD2 (0.40) | SIGMAR1HTR2BSMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL31465869 | 0.88 | SIGMAR1 (0.52) | SIGMAR1HTR2BKCNH2 | |
| SCHEMBL31466156 | 0.87 | HTR4 (0.42) | SMN1; SMN2L3MBTL1NPC1LMNATP53 | |
| SCHEMBL31466615 | 0.86 | SIGMAR1 (0.45) | SIGMAR1HTR2BSMN1; SMN2KCNH2KDM4E | |
| SCHEMBL31466107 | 0.85 | SIGMAR1 (0.44) | SIGMAR1HTR2BKCNH2KDM4E | |
| SCHEMBL31465980 | 0.82 | SIGMAR1 (0.44) | SIGMAR1HTR2BKCNH2ALDH1A1MEN1 | |
| SCHEMBL31465985 | 0.82 | ABL1 (0.46) | SIGMAR1HTR2BKCNH2 | |
| SCHEMBL14686768 | 0.80 | PRCP (0.57) | SIGMAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL31466386 | 0.76 | SIGMAR1 (0.78) | SIGMAR1HTR2BKCNH2 | |
| SCHEMBL31466032 | 0.75 | NPC1 (0.51) | SIGMAR1SMN1; SMN2NPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |