Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31466107 | 0.90 | SIGMAR1 (0.44) | SIGMAR1KCNH2HTR2BKDM4E | |
| SCHEMBL31465869 | 0.86 | SIGMAR1 (0.52) | SIGMAR1KCNH2HTR2B | |
| SCHEMBL31465843 | 0.86 | SIGMAR1 (0.47) | SIGMAR1KCNH2HTR2BKDM4EHPGD | |
| SCHEMBL31465985 | 0.83 | ABL1 (0.46) | SIGMAR1KCNH2HTR2B | |
| SCHEMBL31465980 | 0.81 | SIGMAR1 (0.44) | SIGMAR1KCNH2HTR2B | |
| SCHEMBL31466526 | 0.79 | DRD2 (0.40) | SIGMAR1KCNH2HTR2BSMN1; SMN2 | |
| SCHEMBL31465850 | 0.77 | GABRA1 (0.40) | KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL31466156 | 0.74 | HTR4 (0.42) | KCNH2SMN1; SMN2 | |
| SCHEMBL31465915 | 0.74 | MEN1 (0.48) | NPSR1KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL31466504 | 0.73 | SLC6A4 (0.43) | SIGMAR1CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |