Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18762842 | 0.83 | SIGMAR1 (0.61) | NOS1NOS3SIGMAR1TAAR1HTR7 | |
| SCHEMBL18798802 | 0.80 | LMNA (0.50) | NOS1ACHELMNA | |
| SCHEMBL10339219 | 0.79 | CA2 (0.54) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9670825 | 0.77 | SIGMAR1 (0.70) | NOS1NOS3SIGMAR1TAAR1HTR7 | |
| SCHEMBL28031258 | 0.77 | HDAC1 (0.50) | NOS1SIGMAR1AOC3LMNA | |
| SCHEMBL1561556 | 0.76 | CYP4F2 (0.49) | NOS1NOS3LMNANOS2 | |
| SCHEMBL10750679 | 0.76 | NOS1 (0.50) | NOS1ACHEFDPSAOC3GRIN2D | |
| SCHEMBL4633328 | 0.75 | MAOA (0.55) | NOS1NOS3SIGMAR1TAAR1HTR7 | |
| SCHEMBL5336469 | 0.75 | DRD2 (0.57) | SIGMAR1TAAR1 | |
| SCHEMBL29351393 | 0.74 | CA2 (0.45) | NOS1NOS3LMNANOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |