Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28178606 | 0.94 | PRSS1 (0.38) | SMN1; SMN2PRSS1F2PRSS2PRSS3 | |
| SCHEMBL399197 | 0.84 | KIF11 (0.48) | KIF11HTTSMN1; SMN2L3MBTL1PRSS1 | |
| SCHEMBL3785285 | 0.78 | AOC3 (0.45) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL1743186 | 0.78 | ADRA2A (0.50) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL1996992 | 0.77 | F2 (0.50) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL327252 | 0.76 | LOXL2 (0.54) | PRSS1ST14PLGPLAUPLAT | |
| SCHEMBL27846380 | 0.76 | WDR5 (0.54) | HTTSMN1; SMN2PRSS1PRSS2PRSS3 | |
| SCHEMBL20553484 | 0.76 | PRSS1 (0.54) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL27114626 | 0.76 | MAPT (0.50) | KIF11HTTSMN1; SMN2L3MBTL1PRSS1 | |
| SCHEMBL3772999 | 0.75 | GRIN2D (0.58) | SMN1; SMN2L3MBTL1PRSS1F2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119661535-A | 7H-pyrrolo [3,2-f ] quinazoline derivatives and anti-infective application thereof | 中国医学科学院药物研究所 | 2025-03-21 | — | — | CN | disclosed |