Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxymethane SCHEMBL28287621 | 0.62 | — | — | |
| Methoxymethane SCHEMBL28255990 | 0.62 | — | — | |
| Methoxymethane SCHEMBL28199675 | 0.62 | — | — | |
| Methoxymethane SCHEMBL16998540 | 0.57 | — | — | |
| Methoxymethane SCHEMBL5707121 | 0.57 | — | — | |
| Methoxymethane SCHEMBL868 | 0.57 | — | — | |
| Methoxymethane SCHEMBL12190176 | 0.57 | — | — | |
| SCHEMBL127311 | 0.54 | — | — | |
| Methoxymethane SCHEMBL23668283 | 0.51 | — | — | |
| Methoxymethane SCHEMBL1347303 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514833-A | Deuterated compound and synthesis method and medical application thereof | 南京联智医药科技有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-111732531-B | Method for preparing levamlodipine | 常州瑞明药业有限公司 | 2021-04-23 | — | — | CN | claimed |
| CN-111732531-A | Method for preparing levamlodipine | 史卫明 | 2020-10-02 | — | — | CN | claimed |
| CN-117682985-A | Preparation method of betahistine hydrochloride | 上海佰利源医药科技有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-114773422-B | Preparation method of cholesterol impurity | 湖南科瑞生物制药股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-116514833-A | Deuterated compound and synthesis method and medical application thereof | 南京联智医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-114773422-A | Preparation method of cholesterol impurity | 湖南科瑞生物制药股份有限公司 | 2022-07-22 | — | — | CN | disclosed |
| US-20210206932-A1 | ACTIVATION METHOD USING MODIFYING AGENT | THE BOEING COMPANY | 2021-07-08 | — | — | US | disclosed |
| CN-111732531-B | Method for preparing levamlodipine | 常州瑞明药业有限公司 | 2021-04-23 | — | — | CN | disclosed |
| US-10888896-B2 | Activation method using modifying agent | THE BOEING COMPANY (US) | 2021-01-12 | — | — | US | disclosed |
| CN-111732531-A | Method for preparing levamlodipine | 史卫明 | 2020-10-02 | — | — | CN | disclosed |
| US-20080050598-A1 | Activation method using modifying agent | THE BOEING COMPANY | 2008-02-28 | — | — | US | disclosed |
| EP-1828335-A1 | ACTIVATION METHOD USING MODIFYING AGENT | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006086828-A1 | ACTIVATION METHOD USING MODIFYING AGENT | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2006-08-24 | — | — | WO | disclosed |
| EP-0260121-B1 | INOSOSE DERIVATIVES, PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-5004838-A | Inosose derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-04-02 | — | — | US | disclosed |
| US-4898986-A | Inosose derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0260121-A2 | Inosose derivatives, production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1988-03-16 | — | — | EP | disclosed |
| US-4092310-A | Difluorosteroids and processes for their manufacture | CIBA-GEIGY CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |
| US-3950427-A | ANTIINFLAMMATORY, ANTIPYRETIC | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |