Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL28759042 | 0.94 | MAPK1 (0.40) | MAPK1GSK3AGSK3BHSD17B10PKM | |
| SCHEMBL28759036 | 0.84 | FOLH1 (0.37) | HSD17B10ALOX15ALDH1A1CYP19A1 | |
| SCHEMBL4416473 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL15007041 | 0.81 | FOLH1 (0.38) | CYP19A1 | |
| SCHEMBL19821311 | 0.81 | FOLH1 (0.36) | HSD17B10ALOX15ALDH1A1CYP19A1 | |
| SCHEMBL10082082 | 0.80 | TNF (0.46) | PTGS2GAA | |
| SCHEMBL16586879 | 0.78 | NPSR1 (0.43) | PKMCYP19A1 | |
| SCHEMBL1093819 | 0.76 | GSK3A (0.44) | MAPK1GSK3AGSK3BHSD17B10PIN1 | |
| SCHEMBL10633527 | 0.76 | HSD17B10 (0.61) | MAPK1GSK3AGSK3BHSD17B10PKM | |
| SCHEMBL2360786 | 0.76 | FOLH1 (0.39) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114616227-B | Nitrification inhibitor | 墨尔本大学 | 2025-01-21 | — | — | CN | disclosed |
| CN-111825689-B | Crystal form of dihydropyrazolone compound and preparation method thereof | 中国医药研究开发中心有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-109694380-B | Dihydropyrazolone compound and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-111825690-B | Novel crystal form of PHD inhibitor and preparation method thereof | 中国医药研究开发中心有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-114616227-A | Nitrification inhibitors | 墨尔本大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-111825690-A | Novel crystal form of PHD inhibitor and preparation method thereof | 中国医药研究开发中心有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-111825689-A | Novel crystal form of dihydropyrazolone compound and preparation method thereof | 中国医药研究开发中心有限公司 | 2020-10-27 | — | — | CN | disclosed |
| US-10358454-B2 | Marinopyrrole derivatives and methods of making and using same | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2019-07-23 | — | — | US | disclosed |
| US-10301289-B2 | Method for the preparation of triazole compounds | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-05-28 | — | — | US | disclosed |
| US-10301289-B2 | Method for the preparation of triazole compounds | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-05-28 | — | — | US | disclosed |
| US-20070082890-A1 | Substituted imidazo-[1,5-a][1,2,4]triazolo[1,5-d][1,4] benzodiazepine derivatives | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2007-04-12 | — | — | US | disclosed |
| WO-2006123242-A1 | 1, 2, 4 -TRIAZOLE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | PFIZER LIMITED (GB) | 2006-11-23 | — | — | WO | disclosed |
| WO-2006123242-A1 | 1, 2, 4 -TRIAZOLE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | PFIZER LIMITED (GB) | 2006-11-23 | — | — | WO | disclosed |
| WO-2006114706-A1 | TRIAZOLE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | PFIZER LIMITED (GB) | 2006-11-02 | — | — | WO | disclosed |
| EP-1701959-A1 | TRIAZOLE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | Pfizer Limited (GB) | 2006-09-20 | — | — | EP | disclosed |
| EP-1641788-A1 | PREPARATION OF N2-ALKYLATED 1,2,3-TRIAZOLES | Warner-Lambert Company LLC (US) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005063754-A1 | TRIAZOLE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | PFIZER LIMITED (GB) | 2005-07-14 | — | — | WO | disclosed |
| US-20050154024-A1 | Compounds useful in therapy | PFIZER INC | 2005-07-14 | — | — | US | disclosed |
| WO-2005000841-A1 | PREPARATION OF N2-ALKYLATED 1,2,3-TRIAZOLES | WARNER-LAMBERT COMPANY LLC (US) | 2005-01-06 | — | — | WO | disclosed |
| US-20040266848-A1 | Preparation of N2-alkylated 1,2,3-triazoles | HADD MARK ALLEN (US) | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266848-A1 | Preparation of N2-alkylated 1,2,3-triazoles | PPARA, PPARG, PPARD | MAPK1 1958/4885GSK3A 3127/4885GSK3B 3609/4885 |
| US-10301289-B2 | Method for the preparation of triazole compounds | CYP4B1, BRI3BP, BRD4 | MAPK1 655/4885GSK3A 3962/4885GSK3B 3099/4885 |
| US-20050154024-A1 | Compounds useful in therapy | PTGER4, PTGER3, ALOX5 | MAPK1 3698/4885GSK3A 4478/4885GSK3B 4378/4885 |
| US-20070082890-A1 | Substituted imidazo-[1,5-a][1,2,4]triazolo[1,5-d][1,4] benzodiazepine derivatives | GABRA5, GABRA1, GABRA4 | MAPK1 1695/4885GSK3A 1042/4885GSK3B 1236/4885 |
| US-10358454-B2 | Marinopyrrole derivatives and methods of making and using same | MAP2K3, MDN1, POLR1C | MAPK1 443/4885GSK3A 2214/4885GSK3B 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.