Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567123 | 0.90 | MTNR1B (0.54) | LMNAL3MBTL1MTNR1BMAPTALDH1A1 | |
| SCHEMBL30567097 | 0.85 | L3MBTL1 (0.60) | LMNAL3MBTL1MAPTALDH1A1KDM4E | |
| SCHEMBL31522180 | 0.82 | MTNR1B (0.50) | LMNAL3MBTL1MTNR1BMAPTALDH1A1 | |
| SCHEMBL31522166 | 0.80 | LMNA (0.50) | LMNAL3MBTL1MTNR1BMAPTALDH1A1 | |
| SCHEMBL25386658 | 0.77 | MTNR1B (0.59) | LMNAL3MBTL1MTNR1BMAPTALDH1A1 | |
| SCHEMBL25386654 | 0.77 | MTNR1B (0.59) | LMNAL3MBTL1MTNR1BMAPTALDH1A1 | |
| SCHEMBL8347748 | 0.76 | PGR (0.53) | LMNAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31522182 | 0.75 | POLB (0.44) | LMNAL3MBTL1MTNR1BALDH1A1KDM4E | |
| SCHEMBL31522171 | 0.74 | KDR (0.42) | LMNAL3MBTL1MTNR1BMAPTLPAR1 | |
| SCHEMBL15020425 | 0.74 | HPGD (0.51) | LMNAMAPTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054318-A1 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2025-03-13 | — | — | WO | disclosed |