Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641518 | 0.88 | ALDH1A1 (0.57) | TRPV4ALDH1A1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL10638959 | 0.84 | ALDH1A1 (0.46) | TRPV4ALDH1A1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL20057557 | 0.83 | TRPV4 (0.47) | TRPV4ALDH1A1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL1611864 | 0.81 | L3MBTL1 (0.46) | TRPV4ALDH1A1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL1127669 | 0.77 | KDM4E (0.59) | TRPV4SMN1; SMN2POLBTSHRKDM4E | |
| SCHEMBL4192386 | 0.75 | SMN1; SMN2 (0.51) | TRPV4ALDH1A1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL5012595 | 0.75 | SMN1; SMN2 (0.59) | TRPV4ALDH1A1SMN1; SMN2POLBTSHR | |
| SCHEMBL407215 | 0.75 | L3MBTL1 (0.64) | TRPV4ALDH1A1SMN1; SMN2NPSR1CA1 | |
| SCHEMBL750886 | 0.75 | TRPV4 (0.73) | TRPV4ALDH1A1SMN1; SMN2POLBNPSR1 | |
| SCHEMBL38243330 | 0.75 | TRPV4 (0.73) | TRPV4ALDH1A1SMN1; SMN2POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122182-A1 | MYST Inhibitors | Isosterix, Inc. | 2025-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122182-A1 | MYST Inhibitors | MNAT1, SUGT1, ACAT2 | TRPV4 4752/4885ALDH1A1 3906/4885SMN1; SMN2 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.