Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 8/20 | 0.75 |
| ▸ | HTR1A | P08908 | 7/20 | 0.75 |
| ▸ | HTR2A | P28223 | 7/20 | 0.75 |
| ▸ | HTR6 | P50406 | 4/20 | 0.75 |
| ▸ | HTR1B | P28222 | 4/20 | 0.75 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.75 |
| ▸ | HTR3B | O95264 | 2/20 | 0.75 |
| ▸ | HTR2C | P28335 | 2/20 | 0.75 |
| ▸ | HTR1E | P28566 | 2/20 | 0.75 |
| ▸ | HTR1F | P30939 | 2/20 | 0.75 |
| ▸ | HTR7 | P34969 | 2/20 | 0.75 |
| ▸ | HTR2B | P41595 | 2/20 | 0.75 |
| ▸ | HTR3A | P46098 | 2/20 | 0.75 |
| ▸ | HTR5A | P47898 | 2/20 | 0.75 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.75 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.75 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.75 |
| ▸ | MPO | P05164 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31579517 | 0.88 | HTR1D (0.78) | HTR1DHTR1AHTR2AHTR6HTR1B | |
| SCHEMBL20970975 | 0.86 | HTR1D (1.00) | HTR1DHTR1AHTR2AHTR6HTR1B | |
| SCHEMBL29633037 | 0.86 | HTR1D (1.00) | HTR1DHTR1AHTR2AHTR6HTR1B | |
| SCHEMBL31579687 | 0.82 | HTR1D (0.73) | HTR1DHTR1AHTR2AHTR6HTR1B | |
| SCHEMBL31579279 | 0.82 | HTR1D (0.82) | HTR1DHTR1AHTR2AHTR6HTR1B | |
| SCHEMBL31579547 | 0.81 | HTR1D (0.76) | HTR1DHTR1AHTR2AHTR6HTR1B | |
| SCHEMBL23069123 | 0.80 | HTR1D (1.00) | HTR1DHTR1AHTR2AHTR6HTR1B | |
| SCHEMBL30916160 | 0.80 | MPO (1.00) | HTR1DHTR1AHTR2AHTR6HTR1B | |
| SCHEMBL31176578 | 0.80 | HTR1D (0.69) | HTR1DHTR1AHTR2AHTR6HTR1B | |
| Hydrochloric Acid SCHEMBL5635171 | 0.78 | HTR1A (0.68) | HTR1DHTR1AHTR2AHTR6HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260092035-A1 | INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC (CA) | 2026-04-02 | — | — | US | disclosed |
| US-20250257034-A1 | INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC (CA) | 2025-08-14 | — | — | US | disclosed |
| WO-2025104490-A1 | INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC. (CA) | 2025-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250257034-A1 | INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | TPH1, TPH2, HTR5A | HTR1D 21/4885HTR1A 5/4885HTR2A 8/4885 |
| US-20260092035-A1 | INDOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | HTR6, HTR3C, CNR1 | HTR1D 11/4885HTR1A 7/4885HTR2A 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.