Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649427 | 0.91 | ALDH1A1 (0.46) | TACR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL31649444 | 0.90 | BCHE (0.41) | TACR1ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL31649309 | 0.88 | ACHE (0.43) | TACR1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL31649352 | 0.84 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1KDM1AMAOA | |
| SCHEMBL31649296 | 0.84 | HTR2A (0.40) | MEN1KMT2AHTR2AALDH1A1KDM4E | |
| SCHEMBL31649336 | 0.83 | TACR1 (0.47) | TACR1MEN1KMT2AKDM4EEPHX2 | |
| SCHEMBL31649407 | 0.81 | ALDH1A1 (0.41) | TACR1MEN1KMT2AALDH1A1PRMT5 | |
| SCHEMBL31649382 | 0.81 | KMT2A (0.38) | MEN1KMT2AALDH1A1NPSR1KDM1A | |
| SCHEMBL31649442 | 0.80 | PRSS1 (0.41) | TACR1MEN1KMT2APRMT5WDR77 | |
| SCHEMBL31649410 | 0.79 | KMT2A (0.45) | TACR1MEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |