Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661918 | 0.89 | GPR119 (0.34) | GAAHPGDSMN1; SMN2PRMT5 | |
| SCHEMBL31661959 | 0.86 | GAA (0.52) | GAAHPGDSMN1; SMN2 | |
| SCHEMBL31661966 | 0.85 | HPGD (0.39) | GAASCN9AHPGDSMN1; SMN2KMT2A | |
| SCHEMBL31662174 | 0.84 | TRPC6 (0.34) | GAASCN9AROCK2SYKIRAK4 | |
| SCHEMBL31662124 | 0.83 | SCN9A (0.36) | SCN9AROCK2SYKHAO1 | |
| SCHEMBL31662493 | 0.82 | L3MBTL1 (0.41) | SCN9ASYKHAO1MCL1 | |
| SCHEMBL31661864 | 0.81 | SCN9A (0.34) | SCN9AROCK2SYKIRAK4HAO1 | |
| SCHEMBL31662453 | 0.80 | MKNK1 (0.39) | SCN9AROCK2SYKHAO1MCL1 | |
| SCHEMBL31662511 | 0.79 | SYK (0.38) | SCN9ASYKHAO1MCL1 | |
| SCHEMBL31662113 | 0.79 | SCN9A (0.39) | SCN9AROCK2SYKIRAK4HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |