Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662464 | 0.80 | MPO (0.41) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL31662366 | 0.79 | CA1 (0.42) | KDM4ESMN1; SMN2MAPTALDH1A1CYP3A4 | |
| SCHEMBL31662424 | 0.76 | PARP10 (0.48) | MEN1KMT2AALDH1A1ESR1ESR2 | |
| SCHEMBL31662321 | 0.68 | ESR2 (0.39) | KDM4ESMN1; SMN2KMT2AMAPTALDH1A1 | |
| SCHEMBL31662272 | 0.68 | KCNH2 (0.37) | SMN1; SMN2MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL31662628 | 0.67 | KCNH2 (0.36) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL31662623 | 0.67 | MAPT (0.33) | KDM4ESMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL31662394 | 0.66 | CYP11B2 (0.35) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31662594 | 0.65 | MAPT (0.45) | KDM4ESMN1; SMN2MAPTALDH1A1CYP3A4 | |
| SCHEMBL31662396 | 0.64 | POLB (0.38) | KDM4ETP53CYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |