Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL14776390 | 0.98 | LMNA (0.45) | LMNABLMTP53PTPN1ALDH1A1 | |
| SCHEMBL316934 | 0.89 | LMNA (0.54) | LMNABLMPTPN1ALDH1A1MEN1 | |
| SCHEMBL10045743 | 0.89 | LMNA (0.54) | LMNABLMPTPN1ALDH1A1MEN1 | |
| Alcohol SCHEMBL3678305 | 0.87 | LMNA (0.52) | LMNABLMPTPN1ALDH1A1MEN1 | |
| SCHEMBL24555879 | 0.83 | LMNA (0.52) | LMNABLMPTPN1ALDH1A1MEN1 | |
| SCHEMBL317730 | 0.83 | ALDH1A1 (0.46) | LMNABLMPTPN1ALDH1A1MEN1 | |
| SCHEMBL17526511 | 0.83 | ALDH1A1 (0.46) | LMNABLMPTPN1ALDH1A1MEN1 | |
| SCHEMBL17526505 | 0.83 | ALDH1A1 (0.46) | LMNABLMPTPN1ALDH1A1MEN1 | |
| Sulfuric Acid SCHEMBL14776392 | 0.81 | LMNA (0.54) | LMNABLMTP53PTPN1ALDH1A1 | |
| Alcohol SCHEMBL316774 | 0.80 | LMNA (0.37) | LMNABLMTP53PTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299308-B2 | Specific branched aldehydes, alcohols, surfactants, and consumer products based thereon | THE PROCTER & GAMBLE COMPANY (US) | 2012-10-30 | — | — | US | disclosed |
| US-8232432-B2 | Specific branched aldehydes, alcohols, surfactants, and consumer products based thereon | THE PROCTER & GAMBLE COMPANY (US) | 2012-07-31 | — | — | US | disclosed |
| US-20120010423-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | SCHEIBEL JEFFREY JOHN (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010432-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | SCHEIBEL JEFFREY JOHN (US) | 2012-01-12 | — | — | US | disclosed |
| US-8044249-B2 | Specific branched aldehydes, alcohols, surfactants, and consumer products based thereon | THE PROCTER & GAMBLE COMPANY (US) | 2011-10-25 | — | — | US | disclosed |
| US-7994369-B2 | Specific polybranched polyaldehydes, polyalcohols, and surfactants, and consumer products based thereon | THE PROCTER & GAMBLE COMPANY (US) | 2011-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010432-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | ADH5, ADH1A, ADH1C | LMNA 2589/4885BLM 1792/4885TP53 3828/4885 |
| US-20120010423-A1 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon | ADH5, ADH1A, ADH1C | LMNA 2589/4885BLM 1792/4885TP53 3828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.