Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2966536 | 0.76 | DRD2 (0.42) | KMT2AALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL3169396 | 0.74 | MEN1 (0.35) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL7778467 | 0.69 | TSHR (0.47) | ALDH1A1LMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL16463001 | 0.68 | OPRM1 (0.36) | MEN1KMT2ATSHROPRM1SMN1; SMN2 | |
| SCHEMBL9727251 | 0.65 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL16672742 | 0.64 | SMN1; SMN2 (0.51) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL1744701 | 0.63 | CA12 (0.47) | KMT2ATSHRSMN1; SMN2GAA | |
| SCHEMBL7779646 | 0.63 | TSHR (0.41) | ALDH1A1LMNATSHRHTTSMN1; SMN2 | |
| SCHEMBL8950560 | 0.63 | MEN1 (0.43) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8626625 | 0.62 | TSHR (0.40) | MEN1KMT2ALMNATSHROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629084-B2 | Iodine-phenyl-substituted cyclic cetoenols | BAYER CROPSCIENCE AG (DE) | 2014-01-14 | — | — | US | disclosed |
| CN-101056852-B | Iodophenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG | 2013-05-01 | — | — | CN | disclosed |
| CN-101696184-A | iodophenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG | 2010-04-21 | — | — | CN | disclosed |
| CN-101696197-A | Iodophenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG | 2010-04-21 | — | — | CN | disclosed |
| US-20100009850-A1 | Iodine-phenyl-substituted cyclic cetoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
| CN-101056852-A | Iodophenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-10-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009850-A1 | Iodine-phenyl-substituted cyclic cetoenols | KCNE1, KCNH3, KCNH2 | MEN1 3861/4885KMT2A 1203/4885NPSR1 3001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.