SCHEMBL31703444

SCHEMBL31703444

Cc1cc(Oc2cccc(Cl)c2)ccc1N(C)C(=O)CN1CC[C@H](n2cncn2)C1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TACR2 P21452 1/20 0.40
▸ BTK Q06187 2/20 0.36
▸ FFAR1 O14842 1/20 0.36
▸ HRH3 Q9Y5N1 1/20 0.34
▸ FAAH O00519 2/20 0.34
▸ PRCP P42785 1/20 0.34
▸ MGLL Q99685 1/20 0.34
▸ ABL1 P00519 1/20 0.34
▸ EGFR P00533 1/20 0.34
▸ SRC P12931 1/20 0.34
▸ ABL2 P42684 1/20 0.34
▸ GPBAR1 Q8TDU6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31703740 0.89 TACR2 (0.41) TACR2BTKFFAR1HRH3FAAH
SCHEMBL31703416 0.89 TACR2 (0.41) TACR2BTKFFAR1HRH3FAAH
SCHEMBL31703747 0.84 POLB (0.48) HRH3FAAH
SCHEMBL31703966 0.80 IDO1 (0.46) FAAH
SCHEMBL31703486 0.80 IDO1 (0.46) FAAH
SCHEMBL31703383 0.72 MTNR1B (0.50) —
SCHEMBL31703598 0.71 ALDH1A1 (0.47) —
SCHEMBL31703485 0.67 IDO1 (0.45) —
SCHEMBL11244529 0.65 MEN1 (0.55) —
SCHEMBL31703921 0.63 LTA4H (0.54) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217513-A1 ACTIVATION OF PLCG2 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE THE TRUSTEES OF INDIANA UNIVERSITY (US) 2025-10-16 — — WO claimed
WO-2025217513-A1 ACTIVATION OF PLCG2 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE THE TRUSTEES OF INDIANA UNIVERSITY (US) 2025-10-16 — — WO disclosed
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