SCHEMBL31703416

SCHEMBL31703416

CN(C(=O)CN1CC[C@@H](n2cncn2)C1)c1ccc(Oc2cccc(Cl)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TACR2 P21452 1/20 0.41
▸ BTK Q06187 3/20 0.41
▸ MLNR O43193 2/20 0.40
▸ FFAR1 O14842 1/20 0.39
▸ FAAH O00519 4/20 0.38
▸ MGLL Q99685 2/20 0.38
▸ HRH3 Q9Y5N1 2/20 0.38
▸ PRCP P42785 1/20 0.37
▸ DRD4 P21917 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31703740 1.00 TACR2 (0.41) TACR2BTKMLNRFFAR1FAAH
SCHEMBL31703444 0.89 TACR2 (0.40) TACR2BTKFFAR1FAAHMGLL
SCHEMBL31703486 0.83 IDO1 (0.46) FAAH
SCHEMBL31703966 0.83 IDO1 (0.46) FAAH
SCHEMBL31703747 0.81 POLB (0.48) FAAHHRH3
SCHEMBL31703383 0.76 MTNR1B (0.50) —
SCHEMBL31703598 0.75 ALDH1A1 (0.47) —
SCHEMBL31703542 0.68 S1PR1 (0.51) FFAR1DRD4
SCHEMBL31703485 0.68 IDO1 (0.45) —
SCHEMBL31703921 0.67 LTA4H (0.54) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025217513-A1 ACTIVATION OF PLCG2 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE THE TRUSTEES OF INDIANA UNIVERSITY (US) 2025-10-16 — — WO claimed
WO-2025217513-A1 ACTIVATION OF PLCG2 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE THE TRUSTEES OF INDIANA UNIVERSITY (US) 2025-10-16 — — WO disclosed
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