Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3179347 | 0.80 | AKR1C3 (0.36) | AKR1C3AKR1C2ALDH1A1PTGS2KDM4E | |
| SCHEMBL5439558 | 0.76 | TSHR (0.39) | AKR1C3AKR1C2ALDH1A1PTGS2KDM4E | |
| SCHEMBL6838447 | 0.72 | ALDH1A1 (0.36) | AKR1C3AKR1C2ALDH1A1PTGS2KDM4E | |
| SCHEMBL9871803 | 0.72 | KDM4E (0.44) | ALDH1A1KDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL1679346 | 0.71 | AKR1C3 (0.41) | AKR1C3AKR1C2ALDH1A1PTGS2KDM4E | |
| SCHEMBL8167957 | 0.71 | AKR1C3 (0.41) | AKR1C3AKR1C2ALDH1A1PTGS2KDM4E | |
| SCHEMBL6399236 | 0.70 | PTGS2 (0.41) | AKR1C3AKR1C2ALDH1A1PTGS2KDM4E | |
| SCHEMBL7146446 | 0.70 | PTGS2 (0.41) | AKR1C3AKR1C2ALDH1A1PTGS2KDM4E | |
| SCHEMBL7152622 | 0.70 | PTGS2 (0.41) | AKR1C3AKR1C2ALDH1A1PTGS2KDM4E | |
| SCHEMBL24269954 | 0.69 | GRM1 (0.47) | ALDH1A1KDM4EMEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629084-B2 | Iodine-phenyl-substituted cyclic cetoenols | BAYER CROPSCIENCE AG (DE) | 2014-01-14 | — | — | US | disclosed |
| US-20100009850-A1 | Iodine-phenyl-substituted cyclic cetoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009850-A1 | Iodine-phenyl-substituted cyclic cetoenols | KCNE1, KCNH3, KCNH2 | AKR1C3 184/4885AKR1C2 197/4885ALDH1A1 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.