Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 4/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | IL1B | P01584 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31735441 | 0.88 | DYRK1A (0.43) | DYRK1ANFATC1GSK3BCNR1CNR2 | |
| SCHEMBL13537209 | 0.79 | CNR2 (0.41) | DYRK1ANFATC1GSK3BRENCNR1 | |
| SCHEMBL3349651 | 0.78 | HTR6 (0.41) | DYRK1ANFATC1GSK3BRENASH1L | |
| SCHEMBL3352886 | 0.77 | MAPT (0.42) | ASH1LCNR2KMT2A | |
| SCHEMBL3358037 | 0.75 | ALDH1A1 (0.40) | CNR1CNR2 | |
| SCHEMBL3351825 | 0.75 | ACHE (0.44) | NPSR1 | |
| SCHEMBL3352252 | 0.74 | CACNB4 (0.43) | NPSR1 | |
| SCHEMBL3354038 | 0.74 | NR1H2 (0.46) | — | |
| SCHEMBL27527082 | 0.74 | CYP3A4 (0.41) | — | |
| SCHEMBL13131407 | 0.73 | REN (0.42) | RENCNR1CNR2SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |