Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31748597 | 0.78 | IDO1 (0.38) | GRIK1ALOX5KMODHODH | |
| SCHEMBL31748687 | 0.73 | KCNH2 (0.40) | — | |
| SCHEMBL31748613 | 0.73 | PRKAG1 (0.37) | DHODH | |
| SCHEMBL31748523 | 0.72 | PRKAG1 (0.60) | — | |
| SCHEMBL31748607 | 0.72 | PRKAG1 (0.61) | — | |
| SCHEMBL31748573 | 0.69 | CLK1 (0.44) | GRIK1 | |
| SCHEMBL31748351 | 0.68 | CSNK2A1 (0.40) | GRIK1KMO | |
| SCHEMBL19554684 | 0.66 | GRIK1 (0.34) | GRIK1ALOX5KMODHODH | |
| SCHEMBL31386176 | 0.65 | GPR84 (0.35) | — | |
| SCHEMBL19554382 | 0.64 | TBK1 (0.36) | GRIK1ALOX5KMODHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388571-A1 | AMP-ACTIVATED PROTEIN KINASE MODULATOR COMPOUNDS AND USES THEREOF | BIOLEXIS THERAPEUTICS INC (US) | 2025-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388571-A1 | AMP-ACTIVATED PROTEIN KINASE MODULATOR COMPOUNDS AND USES THEREOF | PRKAB2, PRKAB1, PRKAR2B | GRIK1 1655/4885ALOX5 4816/4885KMO 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.