SCHEMBL3175165

SCHEMBL3175165

COc1cc(CCCC(=O)O)ccc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.67
ALDH1A1 P00352 1/20 0.67
GAA P10253 1/20 0.67
NFKB1 P19838 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
ALOX5 P09917 3/20 0.66
OR51E2 Q9H255 1/20 0.66
MTNR1A P48039 1/20 0.63
MTNR1B P49286 1/20 0.63
TRPV1 Q8NER1 4/20 0.62
TAAR1 Q96RJ0 2/20 0.61
MAPK1 P28482 1/20 0.61
CYP1A2 P05177 2/20 0.60
CYP3A4 P08684 2/20 0.60
CYP2C8 P10632 2/20 0.60
CYP2C9 P11712 2/20 0.60
CYP2B6 P20813 2/20 0.60
CYP2C19 P33261 2/20 0.60
LMNA P02545 1/20 0.59
GLA P06280 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7824983 0.95 ALOX5 (0.71) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL4086224 0.94 ALOX5 (0.70) TSHRALDH1A1GAANFKB1TDP1
Dihydroferulic Acid SCHEMBL347918 0.90 ALOX5 (0.74) TSHRALDH1A1GAANFKB1TDP1
Dihydroferulic Acid SCHEMBL29383405 0.90 ALOX5 (0.74) TSHRALDH1A1GAANFKB1TDP1
Dihydroferulic Acid SCHEMBL30210940 0.90 ALOX5 (0.74) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL10738270 0.89 ALOX5 (0.75) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL27488164 0.88 MTNR1A (0.68) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL5723843 0.88 ALOX5 (0.66) TSHRALDH1A1GAANFKB1TDP1
SCHEMBL503571 0.87 PLAAT3 (0.61) ALDH1A1CYP1A2
SCHEMBL9357796 0.85 GABRA1 (0.55) TSHRALDH1A1GAANFKB1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105381573-B Golf 邓禄普体育用品株式会社 2018-03-09 CN disclosed
CN-103446720-B Golf ball 邓禄普体育用品株式会社 2017-05-10 CN disclosed
CN-105381573-A GOLF BALL DUNLOP SPORTS CO LTD 2016-03-09 CN disclosed
CN-103446722-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-02-17 CN disclosed
CN-103446721-B Golf DUNLOP SPORTS CO., LTD. (JP) 2016-02-17 CN disclosed
CN-103446721-A Golf ball DUNLOP SPORTS CO LTD 2013-12-18 CN disclosed
CN-103446722-A Golf ball DUNLOP SPORTS CO LTD 2013-12-18 CN disclosed
CN-103446720-A Golf ball DUNLOP SPORTS CO LTD 2013-12-18 CN disclosed
US-20100028901-A1 METHOD FOR DIAGNOSING IN VITRO OR EX VIVO PSYCHIATRIC DISORDERS AND/OR INTESTINAL DYSBIOSES AURE (FR) 2010-02-04 US disclosed
US-7223805-B2 Light-resistive dispersant and ink composition containing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-05-29 US disclosed
US-7223355-B2 Functional additive having UV-absorbing substituent and ink composition containing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-05-29 US disclosed
US-7223355-B2 Functional additive having UV-absorbing substituent and ink composition containing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-05-29 US disclosed
EP-0426573-B1 Phenoxypropylamine derivatives or salts thereof and antiulcer agents containing the same TERUMO CORP (JP) 1995-05-24 EP disclosed
US-5037837-A 5-lipoxygenase inhibitor TERUMO KABUSHIKI KAISHA (JP) 1991-08-06 US disclosed
EP-0426573-A2 Phenoxypropylamine derivatives or salts thereof and antiulcer agents containing the same TERUMO KABUSHIKI KAISHA (JP) 1991-05-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100028901-A1 METHOD FOR DIAGNOSING IN VITRO OR EX VIVO PSYCHIATRIC DISORDERS AND/OR INTESTINAL DYSBIOSES DBH, CRH, SI TSHR 3056/4885ALDH1A1 1095/4885GAA 1175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.