Dihydroferulic Acid

Dihydroferulic Acid

SCHEMBL347918

COc1cc(CCC(=O)O)ccc1O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.74
OR51E2 Q9H255 1/20 0.74
TSHR P16473 2/20 0.71
GAA P10253 2/20 0.71
ALDH1A1 P00352 1/20 0.71
NFKB1 P19838 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
TAAR1 Q96RJ0 2/20 0.65
MAPK1 P28482 1/20 0.65
TRPV1 Q8NER1 3/20 0.64
CYP1A2 P05177 2/20 0.63
CYP3A4 P08684 2/20 0.63
CYP2C8 P10632 2/20 0.63
CYP2C9 P11712 2/20 0.63
CYP2B6 P20813 2/20 0.63
CYP2C19 P33261 2/20 0.63
LMNA P02545 1/20 0.63
GLA P06280 1/20 0.63
PTPN1 P18031 1/20 0.61
POLB P06746 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dihydroferulic Acid SCHEMBL29383405 1.00 ALOX5 (0.74) ALOX5OR51E2TSHRGAAALDH1A1
Dihydroferulic Acid SCHEMBL30210940 1.00 ALOX5 (0.74) ALOX5OR51E2TSHRGAAALDH1A1
Dihydroferulic Acid SCHEMBL21378343 0.94 ALOX5 (0.67) ALOX5OR51E2TSHRGAAALDH1A1
SCHEMBL3175165 0.90 TSHR (0.67) ALOX5OR51E2TSHRGAAALDH1A1
SCHEMBL7824983 0.89 ALOX5 (0.71) ALOX5OR51E2TSHRGAAALDH1A1
SCHEMBL28355932 0.88 ALOX5 (0.88) ALOX5OR51E2TSHRGAAALDH1A1
SCHEMBL4086224 0.88 ALOX5 (0.70) ALOX5OR51E2TSHRGAAALDH1A1
SCHEMBL4005549 0.88 ALOX5 (0.86) ALOX5OR51E2TSHRGAAALDH1A1
SCHEMBL3182462 0.87 ALOX5 (0.70) ALOX5OR51E2TSHRGAAALDH1A1
SCHEMBL490726 0.87 GAA (0.71) ALOX5OR51E2TSHRGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 970 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA LLC (US) 2026-04-16 US claimed
US-12582146-B2 Angiotensin-converting enzyme inhibitor, blood pressure-lowering agent, and beverages and food products MARUZEN PHARMACEUTICALS CO., LTD. (JP) 2026-03-24 US claimed
EP-4655410-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE Symrise AG (DE) 2025-12-03 EP claimed
EP-4593859-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION Eresina, LLC (US) 2025-08-06 EP claimed
CN-117265908-B Preparation method of surface sizing agent based on water-resistant phenol compound starch 江南大学 2025-06-24 CN claimed
US-20250109416-A1 METHOD FOR PRODUCING 3-PHENYLPROPIONIC ACID ANALOGUE COMPOUNDS MARUZEN PHARMACEUTICALS CO., LTD. (JP) 2025-04-03 US claimed
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 US claimed
WO-2024156879-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE SYMRISE AG (DE) 2024-08-02 WO claimed
WO-2024156359-A1 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE SYMRISE AG (DE) 2024-08-02 WO claimed
WO-2024073013-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA, LLC (US) 2024-04-04 WO claimed
US-20120016390-A1 BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE KNC NER ACQUISITION SUB, INC. (US) 2012-01-19 US claimed
WO-2012009664-A2 BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE KNC NER ACQUISITION SUB, INC. (US) 2012-01-19 WO claimed
EP-2323502-A1 FLAVAN-3-OL CONTAINING FOODSTUFFS Unilever PLC (GB) 2011-05-25 EP claimed
US-20100316631-A1 Water Soluble Curcumin-Based Compounds THE UAB RESEARCH FOUNDATION (US) 2010-12-16 US claimed
US-20100062131-A1 FLAVAN-3-OL CONTAINING FOODSTUFFS CONOPCO, INC., D/B/A UNILEVER (US) 2010-03-11 US claimed
WO-2010026003-A1 FLAVAN-3-OL CONTAINING FOODSTUFFS UNILEVER PLC (GB) 2010-03-11 WO claimed
WO-2008051474-A1 WATER SOLUBLE CURCUMIN-BASED COMPOUNDS THE UAB RESEARCH FOUNDATION (US) 2008-05-02 WO claimed
EP-1717296-A1 Additives for low sulfur mineral oil distillates, comprising aromatics carrying a hydroxyl group, a methoxy group and an acid function. Clariant Produkte (Deutschland) GmbH (DE) 2006-11-02 EP claimed
US-20060242892-A1 Additives for low-sulfur mineral oil distillates, comprising aromatics which bear a hydroxyl group, a methoxy group and an acid function CLARIANT PRODUKTE (DEUTSCHLAND) GMBH 2006-11-02 US claimed
US-20030199566-A1 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same BIONUTRIGEN CO., LTD. (KR) 2003-10-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250109416-A1 METHOD FOR PRODUCING 3-PHENYLPROPIONIC ACID ANALOGUE COMPOUNDS ME1, PCCA, LDHA ALOX5 66/4885OR51E2 1608/4885TSHR 3517/4885
US-20030199566-A1 Phenolic acid derivatives and composition for preventing or treating blood lipid level-related diseases comprising the same NCEH1, HMGCR, DBH ALOX5 477/4885OR51E2 2978/4885TSHR 891/4885
US-12582146-B2 Angiotensin-converting enzyme inhibitor, blood pressure-lowering agent, and beverages and food products ACE, REN, AGT ALOX5 1089/4885OR51E2 4004/4885TSHR 3146/4885
US-20100062131-A1 FLAVAN-3-OL CONTAINING FOODSTUFFS TAS2R50, TAS2R3, TAS1R3 ALOX5 417/4885OR51E2 80/4885TSHR 1143/4885
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION COL2A1, COLGALT1, PLOD3 ALOX5 130/4885OR51E2 3450/4885TSHR 4804/4885
US-20100316631-A1 Water Soluble Curcumin-Based Compounds BAD, TP53, CD14 ALOX5 234/4885OR51E2 4619/4885TSHR 4844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.