SCHEMBL317577

SCHEMBL317577

COC(=O)c1ccc(CCBr)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4A11 Q02928 2/20 0.66
CYP4F2 P78329 1/20 0.64
LOXL2 Q9Y4K0 1/20 0.61
MAPT P10636 2/20 0.58
CCR6 P51684 1/20 0.55
HKDC1 Q2TB90 1/20 0.55
ALDH1A1 P00352 3/20 0.54
HPGD P15428 2/20 0.54
HSD17B10 Q99714 2/20 0.54
TP53 P04637 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C9 P11712 1/20 0.54
ALOX15 P16050 1/20 0.54
ALOX12 P18054 1/20 0.54
CYP2C19 P33261 1/20 0.54
CKS1B P61024 1/20 0.54
SKP2 Q13309 1/20 0.54
HIF1A Q16665 1/20 0.54
CA1 P00915 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6155241 0.90 CYP4A11 (0.55) CYP4A11CYP4F2LOXL2MAPTCCR6
SCHEMBL2173758 0.89 CYP4A11 (0.75) CYP4A11CYP4F2LOXL2MAPTCCR6
SCHEMBL2162519 0.89 CYP4A11 (0.72) CYP4A11CYP4F2LOXL2MAPTCCR6
SCHEMBL27262281 0.89 MGLL (0.56) CYP4A11CYP4F2LOXL2MAPTCCR6
SCHEMBL70185 0.88 CYP4A11 (0.75) CYP4A11CYP4F2LOXL2MAPTCCR6
SCHEMBL33494 0.84 LOXL2 (0.66) CYP4A11CYP4F2LOXL2MAPTALDH1A1
SCHEMBL4050879 0.82 LOXL2 (0.63) CYP4A11CYP4F2LOXL2MAPTCCR6
SCHEMBL2655571 0.82 CYP4A11 (0.79) CYP4A11CYP4F2LOXL2MAPTCCR6
SCHEMBL1426157 0.82 CYP4A11 (0.68) CYP4A11CYP4F2LOXL2MAPTCCR6
SCHEMBL8867548 0.82 CYP4A11 (0.68) CYP4A11CYP4F2LOXL2MAPTCCR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118619922-A Hydroxamic acid compound, and preparation method and application thereof 郑州大学 2024-09-10 CN claimed
CN-116462729-A Prednisone acetate hapten, artificial antigen and application thereof 华南农业大学 2023-07-21 CN claimed
CN-116425759-A Hapten and artificial antigen for simultaneously detecting various nafil medicines in food and application thereof 华南农业大学 2023-07-14 CN claimed
CN-104610166-A Pyrimidine benzyl hydroxamic acid histone deacetylase inhibitor, and preparation method and application thereof UNIV SHANDONG 2015-05-13 CN claimed
CN-104530078-A Thieno [3, 2-d] pyrimidine derivative and preparation method and application thereof UNIV SHANDONG 2015-04-22 CN claimed
EP-4565565-B1 1,2-SUBSTITUTED 3-OXOPYRAZOLIDINE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES NXERA PHARMA UK LTD (GB) 2026-05-27 EP disclosed
US-20260132111-A1 Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics PROSETTA BIOSCIENCES INC (US) 2026-05-14 US disclosed
US-20260125347-A1 l,2-SUBSTITUTED 3-OXOPYRAZOLIDINE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES NXERA PHARMA UK LIMITED (GB) 2026-05-07 US disclosed
US-12528815-B2 5-amino-8-(4-pyridyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3-one compounds for use against cancer NXERA PHARMA UK LIMITED (GB) 2026-01-20 US disclosed
US-12479797-B2 Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors Jubilant Epicore LLC (US) 2025-11-25 US disclosed
US-12459901-B2 Host-targeted pan-respiratory antiviral small molecule therapeutics PROSETTA BIOSCIENCES, INC. (US) 2025-11-04 US disclosed
EP-3455204-B1 CYCLOPROPYL-AMIDE COMPOUNDS AS DUAL LSD1/HDAC INHIBITORS Jubilant Epicore LLC (US) 2025-10-29 EP disclosed
CN-1030755-A INSECTICIDAL PYRAZOLINES DU PONT (US) 1989-02-01 CN disclosed
US-4753962-A HYPOGLYCEMIC, ANTIOBESITY AGENT BEECHAM GROUP P.L.C. (GB) 1988-06-28 US disclosed
US-4654371-A ANTI-OBESITY, HYPOGLYCEMIA AGENTS BEECHAM GROUP P.L.C. (GB) 1987-03-31 US disclosed
US-4616086-A ANTICOAGULANTS BOEHRINGER MANNHEIM GMBH (DE) 1986-10-07 US disclosed
EP-0179619-A1 Heterocyclic amides ICI AMERICAS INC. (US) 1986-04-30 EP disclosed
US-4478849-A HYPERGLYCEMIC AGENTS BEECHAM GROUP LIMITED (GB) 1984-10-23 US disclosed
EP-0006735-B1 SECONDARY AMINES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE BEECHAM GROUP PLC (GB) 1983-06-15 EP disclosed
EP-0006735-A1 Secondary amines, their preparation, pharmaceutical compositions containing them and their use BEECHAM GROUP PLC (GB) 1980-01-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132111-A1 Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics NCOR1, HAVCR2, NR3C1 CYP4A11 1125/4885CYP4F2 2916/4885LOXL2 2438/4885
US-12479797-B2 Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors HDAC1, HDAC11, HDAC2 CYP4A11 654/4885CYP4F2 1872/4885LOXL2 839/4885
US-12528815-B2 5-amino-8-(4-pyridyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3-one compounds for use against cancer ADORA1, ADORA3, OPRL1 CYP4A11 1791/4885CYP4F2 1930/4885LOXL2 2090/4885
US-12459901-B2 Host-targeted pan-respiratory antiviral small molecule therapeutics MAVS, SARS1, ZC3HAV1 CYP4A11 4227/4885CYP4F2 4657/4885LOXL2 2693/4885
US-20260125347-A1 l,2-SUBSTITUTED 3-OXOPYRAZOLIDINE DERIVATIVES AS PROSTAGLANDIN E2 RECEPTOR 4 (EP4) AGONISTS FOR THE TREATMENT OF GASTROINTESTINAL AND PULMONARY DISEASES PTGER4, PTGER1, OXER1 CYP4A11 231/4885CYP4F2 601/4885LOXL2 197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.