Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29047817 | 0.82 | RXRA (0.36) | NAPRTAKR1C3AKR1C2MAP4K4AKR1C1 | |
| SCHEMBL31759347 | 0.72 | CA1 (0.43) | AKR1C3AKR1C2AKR1C1APPCYP2C9 | |
| SCHEMBL30239786 | 0.70 | SIRT6 (0.40) | NAPRTAKR1C3AKR1C2MAP4K4AKR1C1 | |
| SCHEMBL31759402 | 0.70 | SPR (0.42) | AKR1C3AKR1C2MAP4K4AKR1C1APP | |
| SCHEMBL349552 | 0.69 | NAPRT (0.47) | NAPRTAKR1C3AKR1C2MAP4K4AKR1C1 | |
| SCHEMBL31247665 | 0.69 | NAPRT (0.47) | NAPRTAKR1C3AKR1C2MAP4K4AKR1C1 | |
| SCHEMBL15204492 | 0.69 | AKR1C3 (0.38) | AKR1C3AKR1C2MAP4K4AKR1C1APP | |
| SCHEMBL20819544 | 0.68 | CYP26A1 (0.38) | AKR1C3AKR1C2AKR1C1CYP3A4RARA | |
| SCHEMBL31759499 | 0.68 | AKR1C1 (0.34) | NAPRTAKR1C3AKR1C2AKR1C1APP | |
| SCHEMBL31447288 | 0.68 | HCAR2 (0.31) | AKR1C3AKR1C2MAP4K4AKR1C1SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260007684-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U S INC (US) | 2026-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260007684-A1 | AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | NOD1, NLRP3, NOD2 | NAPRT 3481/4885AKR1C3 314/4885AKR1C2 761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.