SCHEMBL317712

SCHEMBL317712

Cn1ccnc1OS(=O)(=O)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.36
CHRNA4 P43681 1/20 0.36
KMT2A Q03164 3/20 0.36
LPO P22079 1/20 0.34
MCL1 Q07820 1/20 0.34
CHRM1 P11229 2/20 0.32
DRD2 P14416 4/20 0.32
DRD4 P21917 2/20 0.32
DRD3 P35462 2/20 0.32
DRD1 P21728 1/20 0.32
DRD5 P21918 1/20 0.32
FDPS P14324 1/20 0.31
MEN1 O00255 1/20 0.30
CXCR2 P25025 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16107858 0.84 CHRNB2 (0.36) CHRNB2CHRNA4KMT2ALPOMCL1
SCHEMBL1681801 0.80 FPR2 (0.33) KMT2ADRD2DRD4DRD3DRD1
SCHEMBL459536 0.78 CHRNB2 (0.40) CHRNB2CHRNA4KMT2ALPOFDPS
SCHEMBL2830180 0.77 ALDH1A1 (0.46) KMT2ADRD2DRD4DRD3DRD1
SCHEMBL1681893 0.76 LMNA (0.37)
SCHEMBL4620124 0.75 TLR8 (0.31) CHRNB2CHRNA4KMT2A
SCHEMBL3914898 0.75 CHRNB2 (0.41) CHRNB2CHRNA4KMT2ALPOFDPS
SCHEMBL5694205 0.74 L3MBTL1 (0.40) KMT2AFDPSMEN1
SCHEMBL10739013 0.72 KMT2A (0.38) CHRNB2CHRNA4KMT2AMEN1
SCHEMBL3016928 0.71 KMT2A (0.44) CHRNB2CHRNA4KMT2ALPOMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023165966-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION TESA SE (DE) 2023-09-07 WO claimed
CN-111435705-B Repairing agent and repairing method thereof and method for preparing photoelectric film 杭州纤纳光电科技有限公司 2023-04-07 CN claimed
CN-107710462-B Electrochemical hydrogen storage electrode and battery 巴斯夫公司 2022-08-02 CN claimed
CN-113430594-B Application of nitrogen-containing micromolecules and electroplating solution 季华实验室 2022-04-01 CN claimed
US-20210395906-A1 ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY CUSTOMARRAY INC (US) 2021-12-23 US claimed
CN-107615556-B Electrolyte and metal hydride battery 巴斯夫公司 2021-11-02 CN claimed
CN-113214795-A Preparation method of ionic liquid phase-change microcapsule 中国科学院过程工程研究所 2021-08-06 CN claimed
US-20130341561-A1 ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY CUSTOMARRAY, INC. (US) 2013-12-26 US claimed
US-8083945-B2 Fluid storage and purification method and system MATHESON TRI-GAS, INC. (US) 2011-12-27 US claimed
US-20100223208-A1 FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM MATHESON TRI-GAS, INC. (US) 2010-09-02 US claimed
US-7718579-B2 Electrochemical deblocking using a hydrazine derivative COMBIMATRIX CORPORATION (US) 2010-05-18 US claimed
WO-2009126382-A2 SUPERCAPACITORS AND METHODS OF MAKING AND USING SAME GEORGIA TECH RESEARCH CORPORATION (US) 2009-10-15 WO claimed
EP-1869061-A2 ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY Combimatrix Corporation (US) 2007-12-26 EP claimed
EP-1805206-A2 ELECTROCHEMICAL DEBLOCKING USING A HYDRAZINE DERIVATIVE Combimatrix Corporation (US) 2007-07-11 EP claimed
US-20070034513-A1 Electrochemical deblocking solution for electrochemical oligomer synthesis on an electrode array COMBIMATRIX CORPORATION 2007-02-15 US claimed
WO-2006105037-A2 ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY COMBIMATRIX CORPORATION (US) 2006-10-05 WO claimed
WO-2006031814-A2 ELECTROCHEMICAL DEBLOCKING USING A HYDRAZINE DERIVATIVE COMBIMATRIX CORPORATION (US) 2006-03-23 WO claimed
US-20060054511-A1 Electrochemical deblocking using a hydrazine derivative CUSTOMARRAY, INC. 2006-03-16 US claimed
US-20240101999-A1 HIGH EFFICIENCY, SMALL VOLUME NUCLEIC ACID SYNTHESIS THERMO FISHER SCIENTIFIC GENEART GMBH (DE) 2024-03-28 US disclosed
WO-2002014340-A1 PROCESSES FOR THE PREPARATION OF OLIGONUCLEOTIDES_______________ ISIS PHARMACEUTICALS, INC. (US) 2002-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210395906-A1 ELECTROCHEMICAL DEBLOCKING SOLUTION FOR ELECTROCHEMICAL OLIGOMER SYNTHESIS ON AN ELECTRODE ARRAY DNMT1, DNASE1, DNPEP CHRNB2 361/4885CHRNA4 1202/4885KMT2A 3944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.