Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.43 |
| ▸ | HDAC3 known ✓ | O15379 | 1/20 | 0.43 |
| ▸ | HSP90AA1 known ✓ | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 known ✓ | P08238 | 1/20 | 0.39 |
| ▸ | PTGS1 known ✓ | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 known ✓ | P35354 | 2/20 | 0.38 |
| ▸ | TTR known ✓ | P02766 | 1/20 | 0.38 |
| ▸ | AGTR1 known ✓ | P30556 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.96 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | EP300 | Q09472 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318448 | 0.98 | PKM (1.00) | PKMHTTLMNAKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL1651218 | 0.94 | PKM (0.92) | PKMHTTLMNAKDM4EMAPT | |
| SCHEMBL11583446 | 0.81 | PKM (0.70) | PKMHTTLMNAKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL10719596 | 0.78 | PKM (0.61) | PKMHTTKDM4EEP300KAT8 | |
| Hydrochloric Acid SCHEMBL5691548 | 0.78 | PKM (0.61) | PKMHTTKDM4EEP300KAT8 | |
| SCHEMBL10579123 | 0.78 | HTT (0.71) | PKMHTTLMNAKDM4EMAPT | |
| SCHEMBL31634598 | 0.78 | PKM (0.65) | PKMHTTLMNAKDM4EMAPT | |
| SCHEMBL4630376 | 0.78 | HTT (0.71) | PKMHTTLMNAKDM4EMAPT | |
| SCHEMBL7191579 | 0.78 | PKM (0.65) | PKMHTTLMNAKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL20497467 | 0.78 | PKM (0.60) | PKMHTTLMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764201-A | Plant growth regulation | TOMOE KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-08-16 | — | — | US | claimed |
| JP-61215305-A | — | — | None | — | — | JP | disclosed |
| JP-2221201-A | — | — | None | — | — | JP | disclosed |
| EP-3280402-B1 | TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING | BIOMENDICS LLC (US) | 2024-06-05 | — | — | EP | disclosed |
| CN-107847466-B | Formulations and methods for modulating wound healing | 贝欧曼蒂克丝公司 | 2024-02-06 | — | — | CN | disclosed |
| US-11786481-B2 | Formulation and process for modulating wound healing | BioMendics, LLC (US) | 2023-10-17 | — | — | US | disclosed |
| EP-3862029-A1 | STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES | Allergan Industrie, SAS (FR) | 2021-08-11 | — | — | EP | disclosed |
| US-20210228501-A1 | Formulation and Process for Modulating Wound Healing | BioMendics, LLC (US) | 2021-07-29 | — | — | US | disclosed |
| EP-3511028-B1 | STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES | ALLERGAN IND SAS (FR) | 2021-04-07 | — | — | EP | disclosed |
| EP-3682911-A1 | STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES | ALLERGAN, INC. (US) | 2020-07-22 | — | — | EP | disclosed |
| WO-2011086458-A1 | STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES | ALLERGAN INDUSTRIE, SAS (FR) | 2011-07-21 | — | — | WO | disclosed |
| US-20110171311-A1 | STABLE HYDROGEL COMPOSITIONS INCLUDING ADDITIVES | ALLERGAN INDUSTRIE, SAS (FR) | 2011-07-14 | — | — | US | disclosed |
| US-20110171310-A1 | HYDROGEL COMPOSITIONS COMPRISING VASOCONSTRICTING AND ANTI-HEMORRHAGIC AGENTS FOR DERMATOLOGICAL USE | ALLERGAN INDUSTRIE, SAS (FR) | 2011-07-14 | — | — | US | disclosed |
| EP-1538136-B1 | Fertilizer composition to stimulate the absorption of nutritive substances in plants | VALAGRO SPA (IT) | 2006-03-08 | — | — | EP | disclosed |
| WO-2005054156-A1 | FERTILIZER COMPOSITION TO STIMULATE THE ABSORPTION OF NUTRITIVE SUBSTANCES IN PLANTS | VALAGRO S.P.A. (IT) | 2005-06-16 | — | — | WO | disclosed |
| EP-1538136-A1 | Fertilizer composition to stimulate the absorption of nutritive substances in plants | Valagro S.p.A. (IT) | 2005-06-08 | — | — | EP | disclosed |
| US-20050119127-A1 | Fertilizer composition to stimulate the absorption of nutritive substances in plants | VALAGRO S.P.A. (IT) | 2005-06-02 | — | — | US | disclosed |
| JP-H02221201-A | SEED-TREATING AGENT AND TREATING METHOD OF SEED | TOMOE KAGAKU KOGYO KK | 1990-09-04 | — | — | JP | disclosed |
| US-4764201-A | Plant growth regulation | TOMOE KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-08-16 | — | — | US | disclosed |
| JP-S61215305-A | PLANT GROWTH REGULATOR | TOMOE KAGAKU KOGYO KK | 1986-09-25 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11786481-B2 | Formulation and process for modulating wound healing | SQSTM1, ATG7, TFEB | GAA 3092/4885HDAC3 198/4885HSP90AA1 269/4885 |
| US-20210228501-A1 | Formulation and Process for Modulating Wound Healing | ATG7, SQSTM1, ATF4 | GAA 3728/4885HDAC3 245/4885HSP90AA1 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.