Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 8/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5972145 | 0.81 | GPR84 (0.44) | MEN1KMT2A | |
| SCHEMBL27369903 | 0.79 | CETP (0.54) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL7537791 | 0.79 | CETP (0.54) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL17381379 | 0.79 | CETP (0.54) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL28554083 | 0.78 | ALDH1A1 (0.54) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL28556815 | 0.77 | ALDH1A1 (0.52) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL14266012 | 0.76 | EPHX1 (0.43) | MEN1KMT2A | |
| SCHEMBL7634006 | 0.76 | CETP (0.50) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL7641679 | 0.76 | CETP (0.50) | MEN1ALDH1A1HPGDKMT2ASIRT2 | |
| SCHEMBL7765629 | 0.76 | LMNA (0.56) | KMT2ACTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101687769-A | Process for preparing benzyl pentahydroxyhexylcarbamoylundecanoate | SANOFI AVENTIS DEUTSCHLAND | 2010-03-31 | — | — | CN | disclosed |
| CN-101687769-A | Process for preparing benzyl pentahydroxyhexylcarbamoylundecanoate | SANOFI AVENTIS DEUTSCHLAND | 2010-03-31 | — | — | CN | disclosed |
| CN-101687769-A | Process for preparing benzyl pentahydroxyhexylcarbamoylundecanoate | SANOFI AVENTIS DEUTSCHLAND | 2010-03-31 | — | — | CN | disclosed |
| US-7678935-B2 | Esters of pentahydroxyhexylcarbamoyl alkanoic acids | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-03-16 | — | — | US | disclosed |
| US-20090082589-A1 | ESTERS OF PENTAHYDROXYHEXYLCARBAMOYL ALKANOIC ACIDS | SANOFI-AVENTIS DEUTSCHLAND GMBH | 2009-03-26 | — | — | US | disclosed |
| WO-2009000397-A1 | PROCESS FOR PREPARING BENZYL PENTAHYDROXYHEXYLCARBAMOYLUNDECANOATE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-12-31 | — | — | WO | disclosed |
| US-20080319221-A1 | Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-12-25 | — | — | US | disclosed |
| US-20080319218-A1 | Processes for Making and Using Benzyl Pentahydroxyhexylcarbamoylundecanoate | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-12-25 | — | — | US | disclosed |
| US-20080319218-A1 | Processes for Making and Using Benzyl Pentahydroxyhexylcarbamoylundecanoate | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082589-A1 | ESTERS OF PENTAHYDROXYHEXYLCARBAMOYL ALKANOIC ACIDS | FASN, ALKBH3, ACAD11 | TLR2 1665/4885MEN1 1805/4885ALDH1A1 86/4885 |
| US-20080319221-A1 | Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids | FASN, ALKBH3, ACAD11 | TLR2 1665/4885MEN1 1805/4885ALDH1A1 86/4885 |
| US-20080319218-A1 | Processes for Making and Using Benzyl Pentahydroxyhexylcarbamoylundecanoate | HMBS, BLVRB, ALKBH3 | TLR2 4602/4885MEN1 1792/4885ALDH1A1 1320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.