Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 10/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10968152 | 1.00 | DNM1 (0.48) | DNM1HTTSLC22A1CA1CA2 | |
| Sulfuric Acid SCHEMBL2524035 | 0.93 | DNM1 (0.50) | DNM1HTTSLC22A1LSSKMT2A | |
| Sulfuric Acid SCHEMBL4151448 | 0.93 | DNM1 (0.50) | DNM1HTTSLC22A1LSSKMT2A | |
| Sulfuric Acid SCHEMBL27681657 | 0.93 | DNM1 (0.50) | DNM1HTTSLC22A1LSSKMT2A | |
| SCHEMBL331461 | 0.91 | DNM1 (0.48) | DNM1HTTSLC22A1LSSKMT2A | |
| SCHEMBL330578 | 0.91 | DNM1 (0.48) | DNM1HTTSLC22A1LSSKMT2A | |
| SCHEMBL332291 | 0.91 | DNM1 (0.48) | DNM1HTTSLC22A1LSSKMT2A | |
| SCHEMBL330697 | 0.91 | DNM1 (0.48) | DNM1HTTSLC22A1LSSKMT2A | |
| Tributylmethylammonium SCHEMBL1618263 | 0.91 | SLC22A1 (0.39) | DNM1HTTSLC22A1CA1CA2 | |
| Sulfuric Acid SCHEMBL6257863 | 0.89 | LSS (0.48) | DNM1HTTSLC22A1LSSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1812382-B1 | METHOD FOR PRODUCING POLYISOCYANATES | BASF SE (DE) | 2013-01-23 | — | — | EP | claimed |
| US-20090112017-A1 | METHOD FOR PRODUCING POLYISOCYANATES | BASF AKTIENGESSELLSCHAFT (DE) | 2009-04-30 | — | — | US | claimed |
| CN-101056848-A | Process for preparing polyisocyanates | BASF AG (DE) | 2007-10-17 | — | — | CN | claimed |
| EP-3042939-B1 | ADHESIVE COMPOSITION | TOAGOSEI CO LTD (JP) | 2021-06-23 | — | — | EP | disclosed |
| CN-109415602-B | 2-cyanoacrylate-based adhesive composition | 东亚合成株式会社 | 2021-05-25 | — | — | CN | disclosed |
| EP-3042933-B1 | CURABLE RESIN COMPOSITION | TOAGOSEI CO LTD (JP) | 2020-09-30 | — | — | EP | disclosed |
| WO-2020071553-A1 | ADHESIVE COMPOSITION FOR ASSEMBLING SPEAKER, METHOD FOR ASSEMBLING SPEAKER, AND SPEAKER | 東亞合成株式会社 | 2020-04-09 | — | — | WO | disclosed |
| EP-2896668-B1 | 2-CYANOACRYLATE-BASED ADHESIVE COMPOSITION | TOAGOSEI CO LTD (JP) | 2019-11-13 | — | — | EP | disclosed |
| EP-3231818-B1 | TWO-PART CURABLE COMPOSITION | TOAGOSEI CO LTD (JP) | 2019-08-14 | — | — | EP | disclosed |
| EP-2780387-B1 | POLYMERIZABLE COMPOSITION, OPTICAL ARTICLE OBTAINED THEREFROM AND METHOD FOR THE PRODUCTION OF SAID OPTICAL ARTICLE | MITSUI CHEMICALS INC (JP) | 2018-11-07 | — | — | EP | disclosed |
| US-9994662-B2 | Two-part curable composition | TOAGOSEI CO., LTD. (JP) | 2018-06-12 | — | — | US | disclosed |
| US-20140327869-A1 | POLYMERIZABLE COMPOSITION, OPTICAL ARTICLE OBTAINED THEREFROM AND METHOD FOR THE PRODUCTION OF SAID OPTICAL ARTICLE | MITSUI CHEMICALS, INC. | 2014-11-06 | — | — | US | disclosed |
| EP-2780387-A1 | POLYMERIZABLE COMPOSITION, OPTICAL ARTICLE OBTAINED THEREFROM AND METHOD FOR THE PRODUCTION OF SAID OPTICAL ARTICLE | Mitsui Chemicals, Inc. (JP) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013073194-A1 | POLYMERIZABLE COMPOSITION, OPTICAL ARTICLE OBTAINED THEREFROM AND METHOD FOR THE PRODUCTION OF SAID OPTICAL ARTICLE | MITSUI CHEMICALS, INC. (JP) | 2013-05-23 | — | — | WO | disclosed |
| US-7897806-B2 | Reacting primary amines with phosgene in ionic liquid as solvent | BASF AKTIENGESELLSCHAFT (DE) | 2011-03-01 | — | — | US | disclosed |
| US-7659430-B2 | Method for separating hydrogen chloride and phosgene | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-09 | — | — | US | disclosed |
| CN-100577638-C | Process for preparing polyisocyanates | BASF AG | 2010-01-06 | — | — | CN | disclosed |
| US-20090112017-A1 | METHOD FOR PRODUCING POLYISOCYANATES | BASF AKTIENGESSELLSCHAFT (DE) | 2009-04-30 | — | — | US | disclosed |
| US-20070293707-A1 | Method for Separating Hydrogen Chloride and Phosgene | BASF AKTIENGESELLSCHAFT (DE) | 2007-12-20 | — | — | US | disclosed |
| CN-101056848-A | Process for preparing polyisocyanates | BASF AG (DE) | 2007-10-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090112017-A1 | METHOD FOR PRODUCING POLYISOCYANATES | PGLS, INMT, PNMT | DNM1 3850/4885HTT 1805/4885SLC22A1 3135/4885 |
| US-20070293707-A1 | Method for Separating Hydrogen Chloride and Phosgene | PSPH, SLC9B2, HVCN1 | DNM1 4070/4885HTT 569/4885SLC22A1 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.