Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3201833 | 0.85 | KMT2A (0.44) | HSD17B10HSD17B1ALDH1A1 | |
| SCHEMBL528472 | 0.72 | GAA (0.42) | ALDH1A1 | |
| SCHEMBL23376841 | 0.70 | PBRM1 (0.38) | PBRM1CASP1CASP7HSD17B10HSD17B1 | |
| SCHEMBL22852089 | 0.70 | PBRM1 (0.34) | PBRM1CASP1CASP7HSD17B10 | |
| SCHEMBL10187270 | 0.70 | CASP1 (0.38) | PBRM1CASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL24858516 | 0.70 | PBRM1 (0.34) | PBRM1CASP1CASP7HSD17B10HSD17B1 | |
| SCHEMBL527664 | 0.70 | PBRM1 (0.34) | PBRM1CASP1CASP7HSD17B10 | |
| SCHEMBL24490882 | 0.70 | PBRM1 (0.34) | PBRM1CASP1CASP7HSD17B10 | |
| SCHEMBL527206 | 0.70 | S100A4 (0.42) | PBRM1CASP1CASP7HSD17B10CYP1A2 | |
| SCHEMBL1915232 | 0.69 | KMT2A (0.41) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773895-B1 | CATALYSTS FOR OLEFIN POLYMERIZATION OR OLIGOMERIZATION | DU PONT (US) | 2011-12-28 | — | — | EP | disclosed |
| US-7683149-B2 | Catalysts for olefin polymerization or oligomerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-03-23 | — | — | US | disclosed |
| US-20080287621-A1 | Catalysts for olefin polymerization or oligomerization | DUPONT POLYMERS, INC. | 2008-11-20 | — | — | US | disclosed |
| US-7442819-B2 | Catalysts for olefin polymerization or oligomerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-28 | — | — | US | disclosed |
| US-20060009597-A1 | Catalysts for olefin polymerization or oligomerization | DUPONT POLYMERS, INC. | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009597-A1 | Catalysts for olefin polymerization or oligomerization | PPOX, HMOX1, NOD2 | PBRM1 159/4885CASP1 3387/4885CASP7 3860/4885 |
| US-20080287621-A1 | Catalysts for olefin polymerization or oligomerization | PPOX, HMOX1, NOD2 | PBRM1 159/4885CASP1 3387/4885CASP7 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.