Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528472 | 0.86 | GAA (0.42) | KMT2AMEN1MAPK1NPSR1MAOA | |
| SCHEMBL3199887 | 0.85 | PBRM1 (0.35) | HSD17B1ALDH1A1HSD17B10 | |
| SCHEMBL31121556 | 0.84 | GAA (0.41) | KMT2AMEN1MAPK1NPSR1MAOA | |
| SCHEMBL10286474 | 0.80 | KDM4E (0.33) | KMT2AMEN1MAPK1NPSR1MAOA | |
| SCHEMBL7262272 | 0.78 | ALDH1A1 (0.59) | KMT2AMEN1MAPK1MAOBL3MBTL1 | |
| SCHEMBL7262274 | 0.78 | ALDH1A1 (0.59) | KMT2AMEN1MAPK1MAOBL3MBTL1 | |
| SCHEMBL10286576 | 0.77 | MEN1 (0.33) | KMT2AMEN1MAPK1NPSR1MAOA | |
| SCHEMBL10286597 | 0.77 | ALDH1A1 (0.34) | KMT2AMEN1MAPK1NPSR1MAOA | |
| SCHEMBL10286478 | 0.77 | MAOA (0.39) | KMT2AMEN1MAPK1NPSR1MAOA | |
| SCHEMBL10286537 | 0.77 | OPRM1 (0.37) | KMT2AMEN1MAPK1NPSR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168249-B1 | Luminescent polydentate polycyclic compounds for metal ions | ZAVALETA FERNANDEZ DE CORDOVA ANDRES (US) | 2021-11-09 | — | — | US | disclosed |
| US-10633586-B1 | Luminescent polydentate polycyclic compounds for metal ions | ZAVALETA FERNANDEZ DE CORDOVA ANDRES (US) | 2020-04-28 | — | — | US | disclosed |
| US-9823199-B1 | Luminescent polydentate polycyclic compounds for metal ions | Zavaleta Fernandez de Cordova, Andres Nildo (US) | 2017-11-21 | — | — | US | disclosed |
| US-20140073619-A1 | METHOD FOR TREATING CHRONIC PAIN | SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE (US) | 2014-03-13 | — | — | US | disclosed |
| US-20140073619-A1 | METHOD FOR TREATING CHRONIC PAIN | SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE (US) | 2014-03-13 | — | — | US | disclosed |
| US-20120135973-A1 | METHOD FOR TREATING CHRONIC PAIN | SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE (US) | 2012-05-31 | — | — | US | disclosed |
| US-20120135973-A1 | METHOD FOR TREATING CHRONIC PAIN | SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE (US) | 2012-05-31 | — | — | US | disclosed |
| WO-2012033916-A1 | METHOD FOR TREATING CHRONIC PAIN | SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE (US) | 2012-03-15 | — | — | WO | disclosed |
| EP-1773895-B1 | CATALYSTS FOR OLEFIN POLYMERIZATION OR OLIGOMERIZATION | DU PONT (US) | 2011-12-28 | — | — | EP | disclosed |
| US-7683149-B2 | Catalysts for olefin polymerization or oligomerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-03-23 | — | — | US | disclosed |
| US-20080287621-A1 | Catalysts for olefin polymerization or oligomerization | DUPONT POLYMERS, INC. | 2008-11-20 | — | — | US | disclosed |
| US-7442819-B2 | Catalysts for olefin polymerization or oligomerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-28 | — | — | US | disclosed |
| EP-1773895-A2 | CATALYSTS FOR OLEFIN POLYMERIZATION OR OLIGOMERIZATION | E.I.Du pont de nemours and company (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006010065-A2 | CATALYSTS FOR OLEFIN POLYMERIZATION OR OLIGOMERIZATION | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-01-26 | — | — | WO | disclosed |
| US-20060009597-A1 | Catalysts for olefin polymerization or oligomerization | DUPONT POLYMERS, INC. | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135973-A1 | METHOD FOR TREATING CHRONIC PAIN | OPRK1, TRPV1, OPRM1 | KMT2A 2693/4885MEN1 4351/4885MAPK1 4496/4885 |
| US-11168249-B1 | Luminescent polydentate polycyclic compounds for metal ions | PCBP1, CACYBP, CA9 | KMT2A 2733/4885MEN1 388/4885MAPK1 2540/4885 |
| US-20060009597-A1 | Catalysts for olefin polymerization or oligomerization | PPOX, HMOX1, NOD2 | KMT2A 3329/4885MEN1 1011/4885MAPK1 2840/4885 |
| US-20080287621-A1 | Catalysts for olefin polymerization or oligomerization | PPOX, HMOX1, NOD2 | KMT2A 3329/4885MEN1 1011/4885MAPK1 2840/4885 |
| US-20140073619-A1 | METHOD FOR TREATING CHRONIC PAIN | OPRK1, TRPV1, OPRM1 | KMT2A 2693/4885MEN1 4351/4885MAPK1 4496/4885 |
| US-10633586-B1 | Luminescent polydentate polycyclic compounds for metal ions | PCBP1, CACYBP, CA9 | KMT2A 2733/4885MEN1 388/4885MAPK1 2540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.