Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.40 |
| ▸ | MYLK | Q15746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29399700 | 0.79 | ALDH1A1 (0.37) | HTTKDM4EALOX12ALDH1A1TDP1 | |
| SCHEMBL6561982 | 0.79 | ALDH1A1 (0.37) | HTTKDM4EALOX12ALDH1A1TDP1 | |
| SCHEMBL932272 | 0.79 | ALDH1A1 (0.41) | HTTKDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL5513040 | 0.78 | CA2 (0.41) | HTTKDM4ENPC1ALOX12RAB9A | |
| SCHEMBL932105 | 0.78 | KLF10 (0.47) | HTTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL2040206 | 0.78 | GABRA1 (0.43) | HTTALDH1A1TDP1ALOX15HSD17B10 | |
| SCHEMBL70068 | 0.76 | ALDH1A1 (0.48) | HTTKDM4EALOX12NPSR1ALDH1A1 | |
| SCHEMBL30027143 | 0.76 | ALDH1A1 (0.48) | HTTKDM4EALOX12NPSR1ALDH1A1 | |
| SCHEMBL27963029 | 0.76 | ALDH1A1 (0.48) | HTTKDM4EALOX12NPSR1ALDH1A1 | |
| SCHEMBL3175623 | 0.74 | TSHR (0.38) | ALDH1A1MAPTKMT2ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363801-A2 | Process for making 3,5-dialkyl-4-hydroxybenzyl-substituted aromatics | ETHYL CORPORATION (US) | 1990-04-18 | — | — | EP | claimed |
| EP-2662351-B1 | Alkylated heterocyclic reaction products useful as antioxidants | SI GROUP INC (US) | 2016-03-30 | — | — | EP | disclosed |
| EP-2084142-B1 | ALKYLATED HETEROCYCLIC REACTION PRODUCTS USEFUL AS ANTIOXIDANTS | SI GROUP INC (US) | 2016-03-23 | — | — | EP | disclosed |
| CN-101610992-B | Alkylated heterocyclic reaction products useful as antioxidants | ALBEMARLE CORP | 2014-04-16 | — | — | CN | disclosed |
| EP-2662351-A1 | Alkylated heterocyclic reaction products useful as antioxidants | Albemarle Corporation (US) | 2013-11-13 | — | — | EP | disclosed |
| US-8410084-B2 | Alkylated heterocyclic reaction products useful as antioxidants | ALBEMARLE CORPORATION (US) | 2013-04-02 | — | — | US | disclosed |
| US-20100041730-A1 | ALKYLATED HETEROCYCLIC REACTION PRODUCTS USEFUL AS ANTIOXIDANTS | ADDIVANT USA, LLC | 2010-02-18 | — | — | US | disclosed |
| CN-101610992-A | Make the alkylated heterocyclic reaction products useful of antioxidant | ALBEMARLE CORP (US) | 2009-12-23 | — | — | CN | disclosed |
| CN-101528668-A | Macromolecular amine-phenolic antioxidant compositions, process technology thereof, and uses thereof | ALBEMARLE CORP (US) | 2009-09-09 | — | — | CN | disclosed |
| EP-2084142-A2 | ALKYLATED HETEROCYCLIC REACTION PRODUCTS USEFUL AS ANTIOXIDANTS | Albermarle Corporation (US) | 2009-08-05 | — | — | EP | disclosed |
| WO-2009073378-A1 | INDUSTRIAL OIL FORMULATIONS CONTAINING MACROMOLECULAR ANTIOXIDANTS | ALBEMARLE CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |
| WO-2008048988-A2 | ALKYLATED HETEROCYCLIC REACTION PRODUCTS USEFUL AS ANTIOXIDANTS | ALBEMARLE CORPORATION (US) | 2008-04-24 | — | — | WO | disclosed |
| EP-0363801-A2 | Process for making 3,5-dialkyl-4-hydroxybenzyl-substituted aromatics | ETHYL CORPORATION (US) | 1990-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041730-A1 | ALKYLATED HETEROCYCLIC REACTION PRODUCTS USEFUL AS ANTIOXIDANTS | GPX4, AOX1, SQOR | HTT 1778/4885KDM4E 3070/4885NPC1 3811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.