Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463995 | 0.94 | MGAM (0.52) | — | |
| Potassium Ion SCHEMBL344530 | 0.94 | — | — | |
| SCHEMBL3181127 | 0.94 | — | — | |
| Lithium Ion SCHEMBL3197975 | 0.94 | — | — | |
| SCHEMBL3180441 | 0.94 | — | — | |
| SCHEMBL25276832 | 0.94 | MGAM (0.52) | — | |
| Lithium Ion SCHEMBL15950214 | 0.94 | MGAM (0.52) | — | |
| Tetramethylammonium Ion SCHEMBL4772224 | 0.89 | MGAM (0.48) | — | |
| Tetrylammonium SCHEMBL4773294 | 0.83 | MGAM (0.42) | — | |
| Acetoacetic Acid SCHEMBL29060526 | 0.79 | MGAM (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865974-A | Synthesis method of Rhynchines A-E compound | 陕西师范大学 | 2024-04-12 | — | — | CN | claimed |
| EP-1878493-B1 | Method of making a polyisocyanurate/polyurethane foam using carbocation compounds as trimerization catalysts | AIR PROD & CHEM (US) | 2013-08-21 | — | — | EP | claimed |
| US-20080015274-A1 | Stabilized carbanions as trimerization catalysts | EVONIK OPERATIONS GMBH (DE) | 2008-01-17 | — | — | US | claimed |
| EP-1878493-A1 | Stabilized carbanions as trimerization catalysts | Air Products and Chemicals, Inc. (US) | 2008-01-16 | — | — | EP | claimed |
| CN-117865974-A | Synthesis method of Rhynchines A-E compound | 陕西师范大学 | 2024-04-12 | — | — | CN | disclosed |
| US-11680923-B2 | Technologies using surface-modified pseudo-graphite | ABB SCHWEIZ AG (CH) | 2023-06-20 | — | — | US | disclosed |
| US-20230107216-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | VECTIVBIO COMET AG, F/K/A COMET THERAPEUTICS, INC. (CH) | 2023-04-06 | — | — | US | disclosed |
| EP-3887353-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | Comet Therapeutics, Inc. (US) | 2021-10-06 | — | — | EP | disclosed |
| US-20200284751-A1 | Technologies Using Surface-Modified Pseudo-Graphite | ABB SCHWEIZ AG (CH) | 2020-09-10 | — | — | US | disclosed |
| WO-2020113209-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | COMET THERAPEUTICS, INC. (US) | 2020-06-04 | — | — | WO | disclosed |
| EP-1878493-B1 | Method of making a polyisocyanurate/polyurethane foam using carbocation compounds as trimerization catalysts | AIR PROD & CHEM (US) | 2013-08-21 | — | — | EP | disclosed |
| US-8445555-B2 | Stabilized carbanions as trimerization catalysts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-4306079-A | Novel ester derivatives of polycarboxylic acids and process for making same | LEVER BROTHERS COMPANY (US) | 1981-12-15 | — | — | US | disclosed |
| US-4299773-A | Ester derivatives of polycarboxylic acids and process for making same | LEVER BROTHERS COMPANY (US) | 1981-11-10 | — | — | US | disclosed |
| US-4275007-A | β-Lactone esters | LEVER BROTHERS COMPANY (US) | 1981-06-23 | — | — | US | disclosed |
| US-4273935-A | Salts of propene 1,1,2,3-tetracarboxylic acid | LEVER BROTHERS COMPANY (US) | 1981-06-16 | — | — | US | disclosed |
| US-4218381-A | Novel ester derivatives of polycarboxylic acids and process for making same | LEVER BROTHERS COMPANY (US) | 1980-08-19 | — | — | US | disclosed |
| US-4209636-A | Preparation of ester derivatives of polycarboxylic acids | LEVER BROTHERS COMPANY (US) | 1980-06-24 | — | — | US | disclosed |
| US-4159388-A | Ester derivatives of 1-halo-1,1,2,3-propane tetracarboxylic acid | LEVER BROTHERS COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4123458-A | HALOGENATION, DEHYDROGENATION, DECARBOXYLATION | LEVER BROTHERS COMPANY (US) | 1978-10-31 | — | — | US | disclosed |