Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30200499 | 0.98 | CA1 (0.40) | CA1CA2HTTCYP2A6TSHR | |
| SCHEMBL98105 | 0.79 | MEN1 (0.38) | MEN1NPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12679747 | 0.75 | XDH (0.36) | CYP2A6 | |
| SCHEMBL18936175 | 0.73 | CYP2A6 (0.36) | CYP2A6 | |
| SCHEMBL2259743 | 0.72 | HTT (0.37) | HTTCYP2A6 | |
| SCHEMBL15842667 | 0.71 | CYP2A6 (0.50) | CA1CA2HTTCYP2A6CYP1A2 | |
| SCHEMBL18876039 | 0.71 | ALDH1A1 (0.38) | CYP2A6TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL953913 | 0.71 | EED (0.42) | CYP2A6TDP1HTR2AHTR2C | |
| SCHEMBL19631289 | 0.70 | IMPDH2 (0.34) | CYP2A6MAPT | |
| SCHEMBL11364920 | 0.68 | ENPP2 (0.33) | MEN1NPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259241-A1 | 5-HT2A RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Transneural Therapeutics, Inc. (US) | 2024-12-19 | — | — | WO | disclosed |
| CN-117813293-A | Urea derivatives useful for the treatment of cancer | 蝎子疗法股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-112574175-B | Quinoline compound, preparation method and application thereof | 南京长澳医药科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2023-11-02 | — | — | US | disclosed |
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |
| WO-2021057190-A1 | QUINOLINE COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海阳帆医药科技有限公司 | 2021-04-01 | — | — | WO | disclosed |
| WO-2021057190-A1 | QUINOLINE COMPOUNDS, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海阳帆医药科技有限公司 | 2021-04-01 | — | — | WO | disclosed |
| CN-108473498-A | Pyrazolo [1,5a] pyrimidine derivatives as IRAK4 conditioning agents | 豪夫迈·罗氏有限公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-105566262-B | Alkyl amine compound of benzofuran 7 and application thereof | 华东理工大学 | 2017-10-27 | — | — | CN | disclosed |
| US-20160311791-A1 | NOVEL TRICYCLIC CALCIUM SENSING RECEPTOR ANTOGONISTS FOR THE TREATMENT OF OSTEOPOSOSIS | MERCK SHARP & DOHME CORP. (US) | 2016-10-27 | — | — | US | disclosed |
| US-20100035980-A1 | ANTIPARASITIC AGENTS | PFIZER LIMITED (GB) | 2010-02-11 | — | — | US | disclosed |
| US-7645400-B2 | Composition containing carbon nanotubes having a coating | MITSUBISHI RAYON CO., LTD. (JP) | 2010-01-12 | — | — | US | disclosed |
| US-20090321688-A1 | Carbon Nanotube Composition, Composite Having a Coated Film Composed of the Same, and Their Production Methods | MITSUBISHI RAYON CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| US-7622500-B2 | Antiparasitic agents | PFIZER LIMITED (GB) | 2009-11-24 | — | — | US | disclosed |
| US-20080200540-A1 | ANTIPARASITIC AGENTS | PFIZER LIMITED (GB) | 2008-08-21 | — | — | US | disclosed |
| US-20060052509-A1 | Composition containing carbon nanotubes having coating thereof and process for producing them | MITSUBISHI RAYON CO., LTD. (JP) | 2006-03-09 | — | — | US | disclosed |
| EP-0482108-B1 | SUBSTITUTED 2-IMIDAZOLINES AND PREPARATION AND USE THEREOF | NOVO NORDISK AS (DK) | 1996-03-20 | — | — | EP | disclosed |
| US-5262430-A | Antidiabetic agent lowers blood glucose in mammals in type 2 non insulin dependent diabetes | NOVO NORDISK A/S (DK) | 1993-11-16 | — | — | US | disclosed |
| EP-0482108-A1 | SUBSTITUTED 2-IMIDAZOLINES AND PREPARATION AND USE THEREOF. | NOVO NORDISK AS (DK) | 1992-04-29 | — | — | EP | disclosed |
| WO-1991000862-A1 | SUBSTITUTED 2-IMIDAZOLINES AND PREPARATION AND USE THEREOF | NOVO NORDISK A/S (DK) | 1991-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035980-A1 | ANTIPARASITIC AGENTS | ACHE, MPO, ABCB11 | CA1 1663/4885CA2 1451/4885HTT 392/4885 |
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | CA1 4769/4885CA2 4362/4885HTT 334/4885 |
| US-20160311791-A1 | NOVEL TRICYCLIC CALCIUM SENSING RECEPTOR ANTOGONISTS FOR THE TREATMENT OF OSTEOPOSOSIS | CASR, CALCR, CALCRL | CA1 1589/4885CA2 95/4885HTT 4260/4885 |
| US-20080200540-A1 | ANTIPARASITIC AGENTS | ACHE, MPO, ABCB11 | CA1 1663/4885CA2 1451/4885HTT 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.