Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217680 | 0.90 | ALDH1A1 (0.49) | TRPM8IDO1ALDH1A1XBP1HTT | |
| SCHEMBL28300301 | 0.81 | TRPM8 (0.51) | TRPM8MAOAMAOBIDO1RET | |
| SCHEMBL28224648 | 0.81 | TRPM8 (0.51) | TRPM8MAOAMAOBIDO1RET | |
| SCHEMBL9198690 | 0.75 | TRPM8 (0.51) | TRPM8MAOAMAOB | |
| SCHEMBL16162171 | 0.74 | MAOA (0.46) | TRPM8MAOAMAOBIDO1RET | |
| Thiourea SCHEMBL27880910 | 0.73 | IDO1 (0.47) | IDO1PDPK1 | |
| SCHEMBL6895230 | 0.73 | PIN1 (0.50) | IDO1RETHTR2ASIGMAR1PDPK1 | |
| SCHEMBL14527007 | 0.72 | MAOA (0.68) | MAOAMAOBIDO1RETHTR2A | |
| SCHEMBL17571693 | 0.72 | MAOA (0.60) | MAOAMAOBIDO1SIGMAR1PDPK1 | |
| SCHEMBL16356395 | 0.72 | MAOA (0.60) | MAOAMAOBIDO1SIGMAR1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674827-B2 | Indanyl- and tetrahydronaphtyl-amino-thiourea compounds for combating animal pests | BASF SE (DE) | 2010-03-09 | — | — | US | claimed |
| US-20090075819-A1 | Indanyl- and Tetrahydronaphtyl-amino-thiourea Compounds for Combating Animal Pests | BASF SE (DE) | 2009-03-19 | — | — | US | claimed |
| CN-101312945-A | Indanyl- and tetrahydronaphtyl-amino-thiourea compounds for combating animal pests | BASF SE (DE) | 2008-11-26 | — | — | CN | claimed |
| EP-1957447-A1 | INDANYL-AND TETRAHYDRONAPHTYL-AMINO-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-08-20 | — | — | EP | claimed |
| WO-2007060120-A1 | INDANYL-AND TETRAHYDRONAPHTYL-AMINO-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2007-05-31 | — | — | WO | claimed |
| US-7674827-B2 | Indanyl- and tetrahydronaphtyl-amino-thiourea compounds for combating animal pests | BASF SE (DE) | 2010-03-09 | — | — | US | disclosed |
| US-20090075819-A1 | Indanyl- and Tetrahydronaphtyl-amino-thiourea Compounds for Combating Animal Pests | BASF SE (DE) | 2009-03-19 | — | — | US | disclosed |
| CN-101312945-A | Indanyl- and tetrahydronaphtyl-amino-thiourea compounds for combating animal pests | BASF SE (DE) | 2008-11-26 | — | — | CN | disclosed |
| EP-1957447-A1 | INDANYL-AND TETRAHYDRONAPHTYL-AMINO-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007060120-A1 | INDANYL-AND TETRAHYDRONAPHTYL-AMINO-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075819-A1 | Indanyl- and Tetrahydronaphtyl-amino-thiourea Compounds for Combating Animal Pests | AHCYL1, AHCY, TST | TRPM8 3557/4885MAOA 4524/4885MAOB 3995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.