Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421802 | 0.74 | NOS1 (0.35) | NOS1 | |
| SCHEMBL45555 | 0.74 | KDM4E (0.35) | NOS1 | |
| SCHEMBL9996915 | 0.74 | GAA (0.41) | NOS1 | |
| SCHEMBL31224907 | 0.69 | — | — | |
| SCHEMBL17326272 | 0.69 | TRPA1 (0.33) | DYRK1A | |
| SCHEMBL19579757 | 0.68 | KDM4E (0.43) | — | |
| SCHEMBL8014109 | 0.67 | KDM4E (0.43) | NOS1 | |
| SCHEMBL31224914 | 0.67 | ADORA2A (0.32) | — | |
| SCHEMBL31224733 | 0.65 | HPGD (0.43) | — | |
| SCHEMBL3050731 | 0.65 | ALDH1A1 (0.44) | NOS1METAP2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100047321-A1 | SILVER ANTIMICROBIAL COMPOSITION AND USE | EASTMAN KODAK COMPANY | 2010-02-25 | — | — | US | claimed |
| WO-2010021662-A2 | SILVER ANTIMICROBIAL COMPOSITION AND USE | EASTMAN KODAK COMPANY (US) | 2010-02-25 | — | — | WO | claimed |
| EP-0566075-B1 | Silver halide photographic emulsions utilizing low-dye sensitizations with incorporated fog suppressants | EASTMAN KODAK CO (US) | 1998-12-09 | — | — | EP | claimed |
| EP-0566075-A1 | Silver halide photographic emulsions utilizing low-dye sensitizations with incorporated fog suppressants | EASTMAN KODAK COMPANY (US) | 1993-10-20 | — | — | EP | claimed |
| EP-4676926-A1 | BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS | ThirtyFiveBio Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184650-A1 | BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS. | ThirtyFiveBio Limited (GB) | 2024-09-12 | — | — | WO | disclosed |
| CN-109311878-B | Triazolopyridines as gamma-secretase modulators | 豪夫迈·罗氏有限公司 | 2022-05-24 | — | — | CN | disclosed |
| US-10981879-B2 | Thioether triazolopyridine and triazolopyrimidine inhibitors of myeloperoxidase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-04-20 | — | — | US | disclosed |
| US-10407422-B2 | Triazolopyridine inhibitors of myeloperoxidase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-09-10 | — | — | US | disclosed |
| US-10316035-B2 | Triazolopyridine inhibitors of myeloperoxidase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-06-11 | — | — | US | disclosed |
| US-20190031623-A1 | THIOETHER TRIAZOLOPYRIDINE AND TRIAZOLOPYRIMIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL MYERS SQUIBB CO (US) | 2019-01-31 | — | — | US | disclosed |
| US-20190023701-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL MYERS SQUIBB CO (US) | 2019-01-24 | — | — | US | disclosed |
| US-20100047321-A1 | SILVER ANTIMICROBIAL COMPOSITION AND USE | EASTMAN KODAK COMPANY | 2010-02-25 | — | — | US | disclosed |
| WO-2010010189-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |
| US-20090215817-A1 | Novel Triazolopyridine Compounds for the Treatment of Inflammation | PFIZER INC | 2009-08-27 | — | — | US | disclosed |
| US-20090209577-A1 | Novel Triazolopyridine Compounds | PFIZER INC. (US) | 2009-08-20 | — | — | US | disclosed |
| EP-0566075-B1 | Silver halide photographic emulsions utilizing low-dye sensitizations with incorporated fog suppressants | EASTMAN KODAK CO (US) | 1998-12-09 | — | — | EP | disclosed |
| EP-0566075-A1 | Silver halide photographic emulsions utilizing low-dye sensitizations with incorporated fog suppressants | EASTMAN KODAK COMPANY (US) | 1993-10-20 | — | — | EP | disclosed |
| US-5210014-A | Benzimidazole carbocyanine dyes, storage stability | EASTMAN KODAK COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0506077-A1 | Mid-green sensitizing dyes for photographic materials | EASTMAN KODAK COMPANY (US) | 1992-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10316035-B2 | Triazolopyridine inhibitors of myeloperoxidase | EPX, MPO, SERPINB1 | NOS1 477/4885METAP2 221/4885CSNK2A1 1844/4885 |
| US-20190031623-A1 | THIOETHER TRIAZOLOPYRIDINE AND TRIAZOLOPYRIMIDINE INHIBITORS OF MYELOPEROXIDASE | EPX, MPO, SERPINB1 | NOS1 1221/4885METAP2 154/4885CSNK2A1 1627/4885 |
| US-20190023701-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | EPX, MPO, SERPINB1 | NOS1 619/4885METAP2 135/4885CSNK2A1 2093/4885 |
| US-20090209577-A1 | Novel Triazolopyridine Compounds | MAP3K2, MAP3K5, MAP3K9 | NOS1 134/4885METAP2 1505/4885CSNK2A1 713/4885 |
| US-20090215817-A1 | Novel Triazolopyridine Compounds for the Treatment of Inflammation | TNF, MAP3K2, MAP3K5 | NOS1 121/4885METAP2 1761/4885CSNK2A1 864/4885 |
| US-10407422-B2 | Triazolopyridine inhibitors of myeloperoxidase | EPX, MPO, SERPINB1 | NOS1 619/4885METAP2 135/4885CSNK2A1 2093/4885 |
| US-10981879-B2 | Thioether triazolopyridine and triazolopyrimidine inhibitors of myeloperoxidase | EPX, MPO, SERPINB1 | NOS1 1221/4885METAP2 154/4885CSNK2A1 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.