SCHEMBL3206647

SCHEMBL3206647

O=S(=O)(O)c1ccc(F)cc1C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.42
TRPV4 Q9HBA0 2/20 0.40
IDO1 P14902 2/20 0.40
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
CNR1 P21554 2/20 0.38
CNR2 P34972 2/20 0.38
PTGES2 Q9H7Z7 2/20 0.37
HSD11B1 P28845 6/20 0.37
PTPN1 P18031 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27308701 0.98 EPHX2 (0.41) EPHX2TRPV4IDO1CA12CA1
SCHEMBL3203638 0.85 PTGES2 (0.37) EPHX2IDO1PTGES2PTPN1FFAR4
SCHEMBL2747697 0.85 PTGS1 (0.42) PTGES2HSD11B1PTPN1
SCHEMBL30395525 0.81 TRPV4 (0.60) EPHX2TRPV4IDO1CA12CA1
SCHEMBL5831189 0.81 KIF11 (0.44) EPHX2TRPV4IDO1CA12CA1
SCHEMBL795545 0.81 CES2 (0.52) TRPV4CA12CA1CA2CA4
SCHEMBL14600285 0.81 LMNA (0.41) TRPV4CA12CA1CA2CA4
SCHEMBL27921944 0.81 CA12 (0.55) EPHX2TRPV4IDO1CA12CA1
SCHEMBL695151 0.81 TRPV4 (0.60) EPHX2TRPV4IDO1CA12CA1
SCHEMBL10296146 0.79 PFKFB3 (0.41) TRPV4CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11754927-B2 Photoresist pattern trimming compositions and pattern formation methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-09-12 US disclosed
US-11754927-B2 Photoresist pattern trimming compositions and pattern formation methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-09-12 US disclosed
US-20200379353-A1 PHOTORESIST PATTERN TRIMMING COMPOSITIONS AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2020-12-03 US disclosed
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed
US-20020090569-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11754927-B2 Photoresist pattern trimming compositions and pattern formation methods AHR, ALKBH1, CNOT1 EPHX2 2657/4885TRPV4 3825/4885IDO1 294/4885
US-20200379353-A1 PHOTORESIST PATTERN TRIMMING COMPOSITIONS AND PATTERN FORMATION METHODS AHR, ALKBH1, CNOT1 EPHX2 2657/4885TRPV4 3825/4885IDO1 294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.