Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 6/20 | 0.55 |
| ▸ | CA2 | P00918 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911588 | 1.00 | TDP1 (0.69) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL16671924 | 1.00 | TDP1 (0.69) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL17483577 | 1.00 | TDP1 (0.69) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL19243362 | 1.00 | TDP1 (0.69) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL3219136 | 0.98 | TDP1 (0.66) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL5312822 | 0.93 | TDP1 (0.62) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL5162656 | 0.89 | TDP1 (0.85) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL134329 | 0.89 | TDP1 (0.85) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL137629 | 0.89 | TDP1 (0.85) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL343629 | 0.89 | TDP1 (0.85) | TDP1MAOAMAOBMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044744-A2 | PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2024-02-29 | — | — | WO | disclosed |
| US-9867879-B2 | Methods for use of small molecule activators of hem-Y / protoporphyrinogen oxidase (PPO) | VANDERBILT UNIVERSITY (US) | 2018-01-16 | — | — | US | disclosed |
| US-9850275-B2 | Photolabile linker for the solid-phase synthesis of hydrazides and pyranopyrazoles | DANMARKS TEKNISKE UNIVERSITET (DK) | 2017-12-26 | — | — | US | disclosed |
| US-20170246149-A1 | COMPOSITIONS AND METHODS FOR TREATING MICROBIAL INFECTIONS | VANDERBILT UNIVERSITY | 2017-08-31 | — | — | US | disclosed |
| US-20160213780-A1 | METHODS FOR USE OF SMALL MOLECULE ACTIVATORS OF HEM-Y / PROTOPORPHYRINOGEN OXIDASE (PPO) | VANDERBILT UNIVERSITY | 2016-07-28 | — | — | US | disclosed |
| US-9371350-B2 | Trehalose derivatives and pharmaceutical compositions for treating neurodegenerative diseases | POSTECH FOUNDATION (KR) | 2016-06-21 | — | — | US | disclosed |
| US-20150174130-A1 | COMPOSITIONS AND METHODS FOR TREATING MICROBIAL INFECTIONS | VANDERBILT UNIVERSITY | 2015-06-25 | — | — | US | disclosed |
| US-20150025035-A1 | INOSITOL AND TREHALOSE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISEASES COMPRISING THE SAME | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2015-01-22 | — | — | US | disclosed |
| WO-2012024363-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRIDAE VIRAL INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-02-23 | — | — | WO | disclosed |
| US-8058413-B2 | Molecular transporters based on sugar and its analogues and processes for the preparation thereof | POSTECH FOUNDATION (KR) | 2011-11-15 | — | — | US | disclosed |
| US-20100261710-A1 | HDAC Inhibitors | ARQULE, INC. (US) | 2010-10-14 | — | — | US | disclosed |
| US-20100261710-A1 | HDAC Inhibitors | ARQULE, INC. (US) | 2010-10-14 | — | — | US | disclosed |
| CN-101835778-A | Hdac inhibitor | ARQULE INC | 2010-09-15 | — | — | CN | disclosed |
| WO-2009026446-A9 | HDAC INHIBITORS | ARQULE, INC. (US) | 2010-03-11 | — | — | WO | disclosed |
| US-20100048536-A1 | Novel Substituted Diaryl Azepine Derivatives as Integrin Ligands | GENESTE HERVE | 2010-02-25 | — | — | US | disclosed |
| WO-2009026446-A2 | HDAC INHIBITORS | ARQULE, INC. (US) | 2009-02-26 | — | — | WO | disclosed |
| US-20040077638-A1 | Novel integrin receptor antagonists | BASF AKTIENGESELLCHAFT (DE) | 2004-04-22 | — | — | US | disclosed |
| EP-1307443-A2 | NOVEL SUBSTITUTED DIARYL AZEPINE DERIVATIVES AS INTEGRIN LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002051810-A2 | INTEGRIN RECEPTOR LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2002-07-04 | — | — | WO | disclosed |
| WO-2002014320-A2 | NOVEL SUBSTITUTED DIARYL AZEPINE DERIVATIVES AS INTEGRIN LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261710-A1 | HDAC Inhibitors | HDAC5, HDAC1, HDAC4 | TDP1 1200/4885MAOA 1679/4885MAOB 2099/4885 |
| US-20160213780-A1 | METHODS FOR USE OF SMALL MOLECULE ACTIVATORS OF HEM-Y / PROTOPORPHYRINOGEN OXIDASE (PPO) | PPOX, HCCS, HMOX2 | TDP1 4653/4885MAOA 320/4885MAOB 310/4885 |
| US-20100048536-A1 | Novel Substituted Diaryl Azepine Derivatives as Integrin Ligands | ITGB3, ITGAL, ITGB4 | TDP1 4706/4885MAOA 3799/4885MAOB 3870/4885 |
| US-20040077638-A1 | Novel integrin receptor antagonists | ITGB3, ITGAV, ITGA2B | TDP1 4784/4885MAOA 4513/4885MAOB 4490/4885 |
| US-20150025035-A1 | INOSITOL AND TREHALOSE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING NEURODEGENERATIVE DISEASES COMPRISING THE SAME | HTT, TREH, ITPA | TDP1 200/4885MAOA 2060/4885MAOB 1806/4885 |
| US-20150174130-A1 | COMPOSITIONS AND METHODS FOR TREATING MICROBIAL INFECTIONS | HMOX1, HMOX2, HMBS | TDP1 4554/4885MAOA 1336/4885MAOB 968/4885 |
| US-20170246149-A1 | COMPOSITIONS AND METHODS FOR TREATING MICROBIAL INFECTIONS | HMOX1, HMOX2, HMBS | TDP1 4554/4885MAOA 1336/4885MAOB 968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.