Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 6/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 3/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.39 |
| ▸ | TNKS | O95271 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | GALR1 | P47211 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3213139 | 0.80 | HTR2C (0.46) | NOTUMGALR1 | |
| SCHEMBL3215846 | 0.79 | PTGS1 (0.43) | NOTUMPTGS2PTGS1 | |
| SCHEMBL3205015 | 0.78 | L3MBTL1 (0.45) | KIF11NOTUMWNT3ATNKS2PTGS2 | |
| SCHEMBL3200982 | 0.76 | CES2 (0.42) | PARP1 | |
| SCHEMBL13923616 | 0.76 | ALDH1A1 (0.40) | NOTUMWNT3ATNKS2PTGS2CYP1A2 | |
| SCHEMBL13492165 | 0.76 | PTGS1 (0.41) | NOTUMWNT3ATNKS2PTGS2PTGS1 | |
| SCHEMBL13492167 | 0.76 | HTR2C (0.36) | WNT3ATNKS2GALR1CYP2A6 | |
| SCHEMBL2165399 | 0.76 | MAPT (0.39) | NOTUM | |
| SCHEMBL17073804 | 0.76 | NPC1 (0.43) | PTGS2PTGS1 | |
| SCHEMBL979881 | 0.75 | KMT2A (0.45) | BACE1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9930888-B2 | Composition | CONOPCO, INC. (US) | 2018-04-03 | — | — | US | disclosed |
| US-9930888-B2 | Composition | CONOPCO, INC. (US) | 2018-04-03 | — | — | US | disclosed |
| US-20150351393-A1 | COMPOSITION | Conopco, Inc., d/b./a UNILEVER (US) | 2015-12-10 | — | — | US | disclosed |
| US-20150351393-A1 | COMPOSITION | Conopco, Inc., d/b./a UNILEVER (US) | 2015-12-10 | — | — | US | disclosed |
| WO-2014118240-A1 | ANTIMICROBIAL COMPOSITION COMPRISING A LACTAM AND A HYDROTROPE | UNILEVER PLC (GB) | 2014-08-07 | — | — | WO | disclosed |
| US-8586618-B2 | Furanone compounds and lactam analogues thereof | BIOSIGNAL LIMITED (AU) | 2013-11-19 | — | — | US | disclosed |
| US-8586618-B2 | Furanone compounds and lactam analogues thereof | BIOSIGNAL LIMITED (AU) | 2013-11-19 | — | — | US | disclosed |
| US-20100035948-A1 | Furanone compounds and lactam analogues thereof | UNILEVER PLC (GB) | 2010-02-11 | — | — | US | disclosed |
| US-20100035948-A1 | Furanone compounds and lactam analogues thereof | UNILEVER PLC (GB) | 2010-02-11 | — | — | US | disclosed |
| US-20100035948-A1 | Furanone compounds and lactam analogues thereof | UNILEVER PLC (GB) | 2010-02-11 | — | — | US | disclosed |
| WO-2008040097-A1 | FURANONE COMPOUNDS AND LACTAM ANALOGUES THEREOF | BIOSIGNAL LIMITED (AU) | 2008-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150351393-A1 | COMPOSITION | CUTA, HAMP, CLPP | BACE1 1384/4885KIF11 4226/4885NOTUM 2874/4885 |
| US-20100035948-A1 | Furanone compounds and lactam analogues thereof | FDPS, CYP2C19, MRPL21 | BACE1 345/4885KIF11 4519/4885NOTUM 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.