Sugi Predict

Sugi Predict / Compounds / SCHEMBL321565

SCHEMBL321565

SCHEMBL321565

C=CCS(=O)(=O)Nc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ KEAP1 Q14145 2/20 0.47
▸ CA1 P00915 2/20 0.47
▸ CA2 P00918 2/20 0.47
▸ IL1RN P18510 1/20 0.45
▸ ERAP1 Q9NZ08 1/20 0.45
▸ KMT2A Q03164 3/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ PKM P14618 1/20 0.42
▸ HPGD P15428 2/20 0.42
▸ LMNA P02545 1/20 0.42
▸ NR3C2 P08235 1/20 0.42
▸ PGR P06401 1/20 0.41
▸ AR P10275 2/20 0.40
▸ CA12 O43570 1/20 0.39
▸ CA9 Q16790 1/20 0.39
▸ TGM2 P21980 1/20 0.38
▸ HDAC1 Q13547 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11663915 0.82 HPGD (0.40) CA1CA2KMT2AALDH1A1HPGD
SCHEMBL14127844 0.82 CA1 (0.54) KEAP1CA1CA2IL1RNERAP1
SCHEMBL4136706 0.81 HPGD (0.35) CA1CA2KMT2AALDH1A1HPGD
SCHEMBL11131714 0.81 IDO1 (0.54) KEAP1CA1CA2IL1RNERAP1
SCHEMBL3632087 0.80 KMT2A (0.48) CA1CA2KMT2AMEN1ALDH1A1
SCHEMBL11594040 0.79 HTR6 (0.51) CA1CA2KMT2AMEN1ALDH1A1
SCHEMBL1679405 0.78 KIF11 (0.41) CA1CA2KMT2AHPGDLMNA
SCHEMBL7568741 0.78 AR (0.43) KEAP1CA1CA2IL1RNERAP1
SCHEMBL12717441 0.78 SYK (0.42) ALDH1A1HPGDLMNA
SCHEMBL8640577 0.77 CA1 (0.48) KEAP1CA1CA2IL1RNERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2351650-B1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD FOR INFORMATION RECORDING, AND AZO METAL COMPLEX DYE FUJI FILM CORP (JP) 2014-11-05 — — EP disclosed
US-8808824-B2 Optical information recording medium, method of recording information and azo metal complex dye FUJIFILM CORPORATION (JP) 2014-08-19 — — US disclosed
US-8642640-B2 1-phenylpyrrole derivatives EXELIXIS, INC. (US) 2014-02-04 — — US disclosed
EP-2349996-B1 1-PHENYLPYRROLE COMPOUNDS EXELIXIS INC (US) 2014-01-01 — — EP disclosed
US-8394481-B2 Optical information recording medium and azo metal complex dye FUJIFILM CORPORATION (JP) 2013-03-12 — — US disclosed
US-8092890-B2 Optical information recording medium, method of recording information, and azo metal complex dye FUJIFILM CORPORATION (JP) 2012-01-10 — — US disclosed
US-20110263544-A1 1-Phenylpyrrole Derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2011-10-27 — — US disclosed
US-20110202942-A1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD OF RECORDING INFORMATION AND PHOTOSENSITIZER FUJIFILM CORPORATION (JP) 2011-08-18 — — US disclosed
EP-2351650-A1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD FOR INFORMATION RECORDING, AND AZO METAL COMPLEX DYE FUJIFILM Corporation (JP) 2011-08-03 — — EP disclosed
EP-2349996-A1 1-PHENYLPYRROLE COMPOUNDS Exelixis, Inc. (US) 2011-08-03 — — EP disclosed
EP-1470910-A1 Multi-layer hose Asahi Glass Co., Ltd. (JP) 2004-10-27 — — EP disclosed
US-20040191440-A1 A multi-layer hose having a multi-layer structure containing an inner layer made of a fluorocopolymer and an outer layer made of polyamide resin ASAHI GLASS COMPANY LIMITED (JP) 2004-09-30 — — US disclosed
EP-1422219-A1 CYCLIC AMINE COMPOUND Kowa Co., Ltd. (JP) 2004-05-26 — — EP disclosed
US-20030073850-A1 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use ABBOTT LABORATORIES 2003-04-17 — — US disclosed
US-6503935-B1 Treating urinary incontinence or retrograde ejaculation ABBOTT LABORATORIES 2003-01-07 — — US disclosed
EP-0051366-B1 TWO-PART, ANAEROBICALLY-CURING COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-07-18 — — EP disclosed
EP-0051366-A1 Two-part, anaerobically-curing compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-05-12 — — EP disclosed
US-4316000-A PERFLUOROALKYLSULFONANILIDE INITIATOR AND A TERTIARY OR SECONDARY AROMATIC AMINE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-02-16 — — US disclosed
US-4163659-A HERBICIDES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-08-07 — — US disclosed
US-4076519-A N-substituted perfluoroalkanesulfonamides as herbicides MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-02-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263544-A1 1-Phenylpyrrole Derivatives REN, AGTR1, NR3C2 KEAP1 101/4885CA1 4633/4885CA2 2498/4885
US-20030073850-A1 4-Imidazole derivatives of benzyl and restricted benzyl sulfonamides, sulfamides, ureas, carbamates, and amides and their use ADRA1D, ADRB1, ADRA1A KEAP1 3759/4885CA1 2378/4885CA2 1314/4885
US-20110202942-A1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD OF RECORDING INFORMATION AND PHOTOSENSITIZER KCNN4, IK, KCNJ2 KEAP1 2357/4885CA1 95/4885CA2 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.