SCHEMBL3216440

SCHEMBL3216440

O=[N+]([O-])c1cc(Cl)cc2[nH]nnc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHUK O15111 1/20 0.40
PIM3 Q86V86 3/20 0.39
TSHR P16473 3/20 0.37
MAPK1 P28482 2/20 0.37
ALDH1A1 P00352 3/20 0.36
PIM1 P11309 1/20 0.36
VCAM1 P19320 1/20 0.36
MAPT P10636 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
KMT2A Q03164 1/20 0.35
HIF1A Q16665 1/20 0.35
GRIN2D O15399 3/20 0.34
GRIN3B O60391 3/20 0.34
GRIN1 Q05586 3/20 0.34
GRIN2A Q12879 3/20 0.34
GRIN2B Q13224 3/20 0.34
GRIN2C Q14957 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3733557 0.81 TXNRD1 (0.46) TSHRMAPK1ALDH1A1MAPTCYP1A2
SCHEMBL1022548 0.80 GRIN2D (0.47) TSHRALDH1A1MAPTCYP1A2CYP3A4
SCHEMBL18152847 0.80 GPR35 (0.40) PIM3TSHRMAPK1ALDH1A1PIM1
SCHEMBL17348518 0.78 XDH (0.45) PIM3TSHRALDH1A1PIM1VCAM1
SCHEMBL5702704 0.76 GPR35 (0.51) TSHRMAPK1ALDH1A1MAPTCYP1A2
SCHEMBL10398538 0.73 ALDH1A1 (0.44) TSHRMAPK1ALDH1A1MAPTMEN1
SCHEMBL103130 0.72 NOS1 (0.51) TSHRMAPK1ALDH1A1MAPTCYP1A2
SCHEMBL1156230 0.72 HTT (0.46) TSHRALDH1A1CYP1A2CYP3A4MEN1
SCHEMBL5221839 0.72 MAPT (0.47) MAPK1ALDH1A1VCAM1MAPTMEN1
Silver SCHEMBL9168531 0.71 NOS1 (0.50) TSHRMAPK1ALDH1A1MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1403698-B1 Silver halide photographic light-sensitive material comprising a particular dye, a hydrazine derivate and a benzotriazole compound FUJIFILM CORP (JP) 2008-09-03 EP claimed
US-7037641-B2 Silver halide emulsion sheet for detecting track of charged elementary particles, and processing method thereof FUJI PHOTO FILM CO.,LTD. (JP) 2006-05-02 US claimed
US-20050233267-A1 Silver halide emulsion sheet for detecting track of charged elementary particles, and processing method thereof FUJIFILM CORPORATION (JP) 2005-10-20 US claimed
US-6916600-B2 Silver halide emulsion sheet for detecting track of charged elementary particles, and processing method thereof FUJI PHOTO FILM CO., LTD. (JP) 2005-07-12 US claimed
CN-1436317-A Mixtures of organic silver salts in color photothermographic systems EASTMAN KODAK CO (US) 2003-08-13 CN claimed
US-6576414-B1 PKsp of said first organic silver salt is at least 0.5 lower than the pKsp of said second silver salt; high speed, storage stable EASTMAN KODAK COMPANY 2003-06-10 US claimed
US-20030096203-A1 Silver halide emulsion sheet for detecting track of charged elementary particles, and processing method thereof FUJIFILM CORPORATION (JP) 2003-05-22 US claimed
US-6548236-B1 The dye-providing couplers in the multilayers being different in hue, forming at least three dye images of different visible or non-visible colors EASTMAN KODAK COMPANY 2003-04-15 US claimed
EP-1299769-A1 MIXTURES OF ORGANIC SILVER SALTS IN COLOR PHOTOTHERMOGRAPHIC SYSTEMS EASTMAN KODAK COMPANY (US) 2003-04-09 EP claimed
US-6426181-B2 THE SECOND SILVER SALT IS A THERMAL FOG INHIBITOR THAT PREVENTS DESORPTION OF SENSITIZING DYES FROM THE IMAGING SILVER HALIDE GRAINS AND IS PREFERABLY A MERCAPTO-HETEROCYCLIC COMPOUND EASTMAN KODAK COMPANY 2002-07-30 US claimed
US-20020015928-A1 Mixtures of organic silver salts in color photothermographic systems IRVING LYN M (US) 2002-02-07 US claimed
WO-2001096949-A1 MIXTURES OF ORGANIC SILVER SALTS IN COLOR PHOTOTHERMOGRAPHIC SYSTEMS EASTMAN KODAK COMPANY (US) 2001-12-20 WO claimed
US-3970459-A Process for developing a direct reversal silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed
US-20110293683-A1 Silver antimicrobial composition with extended shelf-life CERION TECHNOLOGY, INC. 2011-12-01 US disclosed
US-20100047321-A1 SILVER ANTIMICROBIAL COMPOSITION AND USE EASTMAN KODAK COMPANY 2010-02-25 US disclosed
WO-2010021662-A2 SILVER ANTIMICROBIAL COMPOSITION AND USE EASTMAN KODAK COMPANY (US) 2010-02-25 WO disclosed
US-RE29575-E Cubic regular grain photographic reversal emulsions EASTMAN KODAK COMPANY (US) 1978-03-14 US disclosed
US-4011081-A DIRECT-POSITIVE DOUBLE EXPOSURE PROCESS UTILIZING A PRIMITIVE, UNFOGGED SILVER HALIDE EMULSION CONTAINING AN ELECTRON ACCEPTOR EASTMAN KODAK COMPANY (US) 1977-03-08 US disclosed
US-3970459-A Process for developing a direct reversal silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US disclosed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110293683-A1 Silver antimicrobial composition with extended shelf-life AMPD1, GMPS, GDA CHUK 4649/4885PIM3 3589/4885TSHR 4511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.