SCHEMBL3217870

SCHEMBL3217870

C=C(C(N)=O)S(=O)(=O)CCCCC

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 4/20 0.41
CA2 P00918 6/20 0.39
FAAH O00519 6/20 0.39
CES2 O00748 2/20 0.37
CES1 P23141 1/20 0.37
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4601129 0.98 ENPP2 (0.40) ENPP2CA2FAAHCES2CES1
SCHEMBL4794021 0.79 CA2 (0.45) ENPP2CA2FAAHCES2CES1
SCHEMBL2251339 0.78 ENPP2 (0.44) ENPP2CA2FAAHCES2CES1
SCHEMBL5015091 0.77 CA2 (0.48) CA2FAAHCES2CES1TP53
SCHEMBL10616097 0.76 ENPP2 (0.47) ENPP2CA2FAAHCES2CES1
SCHEMBL2099691 0.74 TDP1 (0.46) CA2FAAHCES2CES1TP53
SCHEMBL4554474 0.74 ENPP2 (0.46) ENPP2CA2FAAHCES2CES1
SCHEMBL8634688 0.73 FAAH (0.48) ENPP2CA2FAAHCES2CES1
SCHEMBL2103322 0.73 EPHX2 (0.47) CA2FAAHCES2CES1
SCHEMBL2100773 0.73 EPHX2 (0.47) CA2FAAHCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447505-A Preparation method of beta-silicon-based amide-carboxylic acid medicine hybrid 安阳师范学院 2024-01-26 CN claimed
EP-1912645-A2 THERAPEUTIC AGENT FOR DIABETES Takeda Pharmaceutical Company Limited (JP) 2008-04-23 EP claimed
WO-2007018314-A2 THERAPEUTIC AGENT FOR DIABETES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-02-15 WO claimed
US-4996360-A Preparation of arylsulfonyl (alkyl) amides ATOCHEM (FR) 1991-02-26 US claimed
CN-117447505-A Preparation method of beta-silicon-based amide-carboxylic acid medicine hybrid 安阳师范学院 2024-01-26 CN disclosed
CN-117447505-A Preparation method of beta-silicon-based amide-carboxylic acid medicine hybrid 安阳师范学院 2024-01-26 CN disclosed
CN-115583961-A Synthetic method of alpha-quaternary carbon beta-silicon-based amide 安阳师范学院 2023-01-10 CN disclosed
CN-115583961-A Synthetic method of alpha-quaternary carbon beta-silicon-based amide 安阳师范学院 2023-01-10 CN disclosed
CN-113527267-B C2 symmetric duplex nitrogen heterocyclic ring fluorocarbon surfactant and preparation of aqueous phase micelle thereof 山东盛安贝新能源有限公司 2022-09-02 CN disclosed
CN-113527264-B Method for synthesizing nitrogen-containing heterocyclic fluorocarbon surfactant by adopting photoreaction-click reaction and preparation of aqueous phase micelle thereof 山东盛安贝新能源有限公司 2022-09-02 CN disclosed
CN-113527267-A C2 symmetric duplex nitrogen heterocyclic ring fluorocarbon surfactant and preparation of aqueous phase micelle thereof 山东盛安贝新能源有限公司 2021-10-22 CN disclosed
CN-113527264-A Method for synthesizing nitrogen-containing heterocyclic fluorocarbon surfactant by adopting photoreaction-click reaction and preparation of aqueous phase micelle thereof 山东盛安贝新能源有限公司 2021-10-22 CN disclosed
EP-2118066-A1 FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA Takeda Pharmaceutical Company Limited (JP) 2009-11-18 EP disclosed
US-20090270631-A1 Therapeutic agent for diabetes ABE HIDENORI 2009-10-29 US disclosed
WO-2008099794-A1 FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-08-21 WO disclosed
EP-1912645-A2 THERAPEUTIC AGENT FOR DIABETES Takeda Pharmaceutical Company Limited (JP) 2008-04-23 EP disclosed
US-20080009530-A1 Therapeutic Agent for Diabetes TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-01-10 US disclosed
WO-2007018314-A2 THERAPEUTIC AGENT FOR DIABETES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-02-15 WO disclosed
US-4996360-A Preparation of arylsulfonyl (alkyl) amides ATOCHEM (FR) 1991-02-26 US disclosed
US-4996360-A Preparation of arylsulfonyl (alkyl) amides ATOCHEM (FR) 1991-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270631-A1 Therapeutic agent for diabetes FABP4, SLC5A1, SLC5A2 ENPP2 887/4885CA2 1474/4885FAAH 1354/4885
US-20080009530-A1 Therapeutic Agent for Diabetes FABP4, SLC5A1, SLC5A2 ENPP2 1163/4885CA2 1306/4885FAAH 955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.